Advances in scattering-based optical imaging technologies offer a new approach to noninvasive point-of-care detection, diagnosis, and monitoring of cancer. Emerging photonics technologies provide a cost-effective means to image tissue in vivo with high resolution in real time. Advancing the clinical potential of these imaging strategies requires the development of optical contrast agents target...

it has been revealed that the surface stress effect plays an important role in the mechanical behavior ofstructures (such as bending, buckling and vibration) when their dimensions are on the order ofnanometer. in addition, recent advances in nanotechnology have proposed several applications fornanoscale shells in different fields. hence, in the present article, within the framework of surfaceel...

Redox homeostasis and signaling are critically important in the regulation of cell function. There are significant challenges in quantitatively measuring intracellular redox potentials, and in this paper, we introduce a new approach. Our approach is based on the use of nanosensors which comprise molecules that sense the local redox potential, assembled on a gold nanoshell. Since the Raman spect...

Developing ultrasensitive Raman nanoprobes is one of the emerging interests in the field of biosensing and bioimaging. Herein, we constructed a new type of surface-enhanced resonance Raman scattering nanoprobe composed of an Ag nanoshell as a surface-enhanced Raman scattering-active nanostructure, which was encapsulated with 4,7,10-trioxa-1,13-tridecanediamine-functionalized graphene oxide as a...

The fluorescence characteristics of a dipole molecule in the vicinity of a spherical multilayered metallic nanoshell (a plasmonic nanomatryoska) of ultra-small dimensions is studied via electrodynamic modeling, where we have computed the fluorescence decay rates, the shifts in emission frequency, and the overall fluorescence yields for molecular dipoles of both tangential and radial orientation...

We demonstrate a strategy for label-free protein detection through monitoring the Surface Enhanced Raman Spectrum of an aptamer probe attached to a gold nanoshell. Low limit of detection and minimal non-specific binding show potential for in vitro and in vivo assays.

Novel Raman tags with various reporter molecules embedded in between gold nanostar (AuNS) and gold nanoshell are developed, showing significantly enhanced surface-enhanced Raman scattering intensity compared to gold nanoparticle-based composites. Immunoassay using these AuNS@tag@shell structures is highly specific with sensitivity down to 0.1 pg mL-1 , and is capable of multiplex detection, mak...

A gold nanoshell-functionalized polymer multilayer nanorocket performs self-propulsion upon the irradiation with NIR light in the absence of chemical fuel. Theoretical simulations reveal that the NIR light-triggered self-thermophoresis drives the propulsion of the nanorocket. The nanorocket also displays -efficient NIR light-triggered propulsion in -biofluids and thus holds considerable promise...