The plasmonic properties of noble metal nanoparticles facilitate their use in novel in-vivo bio-applications such as targeted drug delivery and cancer cell therapy. Nanosilver is best suited for such applications as it has the lowest plasmonic losses among all such materials in the UVvisible spectrum. Its toxicity, however, can destroy the surrounding healthy tissue and thus, hinders its safe e...

BACKGROUND Nanosilver shows great promise for use in industrial, consumer or medical products because of its antimicrobial properties. However, the underlying mechanisms of the effects of silver nanoparticles on human cells are still controversial. Therefore, in the present study the influence of the chloride concentration and different serum content of culture media on the cytotoxic effects of...

Mesoporous calcium-silicate nanoparticles (MCSNs) are advanced biomaterials for controlled drug delivery and mineralization induction. Nanosilver-incorporated MCSNs (Ag-MCSNs) were prepared in the present study using both the adsorption and template methods. Both versions of Ag-MCSNs showed characteristic morphology of mesoporous materials and exhibited sustained release of ions over time. In a...

A nanosilver composite plant medium with a good antimicrobial capability was successfully prepared via a two-step method in this work. First, nanosilver particles were prepared in a silver nitrate (AgNO3) solution by using D-glucose as a reduction reagent at room temperature. The effect of AgNO3 concentration levels on the size of the nanosilver particles was investigated. The sedimentation act...

Nanosilver applications have been implicated in paint, plastic, textile and medical industries. Nanosilver particles absorb sweat and in turn avoid pungent smell of feet. The present study aims to determine the antibacterial activity of Ag-coated different sock fabrics and comparing their efficacy in reducing foot-borne resident bacteria. Synthesize of nanosilver particles was performed in vari...

Extensive consumer exposure to food- and cosmetics-related consumer products containing nanosilver is of public safety concern. Therefore, there is a need for suitable in vitro models and sensitive predictive rapid screening methods to assess their toxicity. Toxicogenomic profile showing subtle changes in gene expressions following nanosilver exposure is a sensitive toxicological endpoint for t...

INTRODUCTION Favorable apical seal of root filling materials is a crucial factor for a successful root canal treatment. The aim of this in vitro study was to compare bacterial and dye microleakage of two root canal filling materials including standard gutta-percha and nanosilver coated gutta-percha, and to evaluate the agreement between results of these two methods. MATERIALS AND METHODS Fift...

STATEMENT OF THE PROBLEM Nanosilver particles have the potential to serve as a bactericidal agent because of the inherent antimicrobial influences of silver ion. The literature confirmed that specific micro-organisms, especially streptococci, have an important role as an etiological factor for caries. PURPOSE The aim of this study was to evaluate the antimicrobial effect of conventional and n...

Nanosilver particles are used in various clinical settings because of their antibacterial properties. However, their safety evaluation when used for gynaecological disorders has not been established. Nanosilver particles were administrated in the vagina of New Zealand rabbits, and the pathological appearance of the surrounding tissue was examined by hematoxylin-eosin staining and transmission e...

BACKGROUND Various materials have been added to mineral trioxide aggregate to enhance its properties. This study was aimed to compare the sealing efficacy of MTA with and without nanosilver using bacterial leakage approach. MATERIAL AND METHODS Seventy canine teeth were prepared and obturated. Then, after apical resection, the root-end cavities were prepared by ultrasonic retrotips. Teeth wer...