viral hepatitis, as an international public health concern, seriously affects communities and health system. in recent years, great strides have been taken for development of new potential tools against viral hepatitis. among these efforts, a valuable strategy introduced new molecules called “aptamers”. aptamers as potential alternatives for antibodies could be directed against any protein in i...

clarithromycin (clm) is a member of macrolide family with broad spectrum antibiotic activity. it is practically insoluble in water and its poor solubility is ph dependent. in this study, series of nanosuspensions containing clm and stabilizer such as hpmc, nacmc, polysorbate 80, poloxamer 188 and polyvinyl alcohol in various ratios were prepared using sonoprecipitation method. briefly, clm was ...

Clarithromycin (CLM) is a member of macrolide family with broad spectrum antibiotic activity. It is practically insoluble in water and its poor solubility is pH dependent. In this study, series of nanosuspensions containing CLM and stabilizer such as HPMC, NaCMC, polysorbate 80, poloxamer 188 and polyvinyl alcohol in various ratios were prepared using sonoprecipitation method. Briefly, CLM was ...

Clarithromycin (CLM) is a member of macrolide family with broad spectrum antibiotic activity. It is practically insoluble in water and its poor solubility is pH dependent. In this study, series of nanosuspensions containing CLM and stabilizer such as HPMC, NaCMC, polysorbate 80, poloxamer 188 and polyvinyl alcohol in various ratios were prepared using sonoprecipitation method. Briefly, CLM was ...

The present study aims to enhance the bioavailability of Blueberry by formulating it as nanosuspension. mainly consists ofanthocyanins which have strong antihyperlipidemic activity but suffers from low causes hindrances in itstherapeutic treat hyperlipidemia. Hence improve its bioavailability, nanosuspension blueberry was prepared. BoxBehnken design applied predict effect independent variables ...

Graphene (G) and graphene oxide (GO) are 2D materials known to possess superior functionalities. This arises from their versatility to tune their electronic, electrochemical, optical, mechanical and thermal properties. However, G and GO can also be easily functionalized with various biomolecules and this has led to numerous graphenerelated biomedical sensing applications. Here we will demonstra...

ABSTRACT
 Objective: In this study, it was aimed to prepare nanosuspensions that contains Indomethacin which is a BCS class II drug. To assess the cumulative impact of chosen variables on nanosuspension properties, 34 factorial design applied and particle size distributions were examined.
 Material Method: solvent/antisolvent method used in preparation suspensions. design. Design-Expe...