This study proposed a new strategy for uncovering the active chemical constituents of a traditional Chinese medicines (TCMs) formula, Chaihu-Shu-Gan-San (CSGS). Metabonomics and chemical profile were integrated in combination with the multivariate statistical analysis (MVA) to discover the chemical constituents which contribute to the antidepressant effect of CSGS. Based upon the difference bet...

Enzymatic conjugation with fatty acids including omega-3 polyunsaturated fatty acids (ω-3 PUFAs) derived from fish oil to three citrus fruit-derived flavonoids: grapefruit extract, naringin, and neohesperidin dihydrochalcone were investigated. The conversions were achieved over 85% under the catalysis of lipase Novozyme 435 in acetone at 45°C at semi-preparative scale. The conjugates were purif...

Fourier transform far-infrared (FT-FIR) was exploited to evaluate the flavonoids content of orange extracts using Soxhlet extraction. The absorbance fingerprint spectra hesperidin and naringin were identified in range 0.5–7 THz. absorption peaks obtained at 1.53, 1.85, 2.46, 3.36, 4.51, 5.35, 6.51, 7.55 THz, respectively. For naringin, observed 0.75, 1.50, 2.29, 3.76, 5.18, 6.48, 8.36 perceptib...

Aster novi-belgii is a perennial ornamental herb native to eastern Canada and the United States of America, cultivated in Ukraine. This species should be considered possible source phenolic compounds, principally hydroxycinnamic acids flavonoids. Therefore, this study, aim was determine these compounds by HPLC-DAD analysis, validation chromatographic method lay scientific technical basis for ut...