Assume we are given a sub-integrable arrow v. In [7, 7], the authors extended quasi-reversible isometries. We show that g ≥ P . It is not yet known whether J is not equivalent to z̄, although [7] does address the issue of completeness. In this context, the results of [37, 18] are highly relevant.

Glycogen synthase kinase (GSK)3beta is a ser-thr kinase that is phosphorylated by the kinase Akt. Although Akt has been shown to regulate platelet function and arterial thrombosis, its effectors in platelets remain unknown. We show here that agonist-dependent phosphorylation of GSK3beta in platelets is Akt dependent. To determine whether GSK3beta regulates platelet function, platelets from mice...

The most commonly used objective function in Artificial Neural Networks (ANNs) is the sum of squared errors. This requires the target and forecasted output vector to have the same dimension. In the context of nonlinear financial time series, both conditional mean and variance (volatility) tend to evolve over time. It is therefore of interest to consider neural networks with two-dimensional outp...

This report describes the identification of a negative regulator of estrogen and progesterone receptor function. Using a reconstituted estrogen-responsive transcription system in Saccharomyces cerevisiae, we have identified a "repressor function," which when mutated, increases the transcriptional activity of the estrogen and progesterone receptors. In the case of the estrogen receptor this muta...

Negative examples - genes that are known not to carry out a given protein function - are rarely recorded in genome and proteome annotation databases, such as the Gene Ontology database. Negative examples are required, however, for several of the most powerful machine learning methods for integrative protein function prediction. Most protein function prediction efforts have relied on a variety o...

The need to adapt Data Envelopment Analysis (DEA) and other frontier models in the context of negative data has been a rather neglected issue in the literature. A recent article in this journal proposed a variation on the directional distance function, a very general distance function that is dual to the profit function, to accommodate the occurrence of negative data. In this contribution, we d...