Objective : The aim of the study was to find the correlation of clinical profile and risk factors of neonatal sepsis with culture proven cases. Materials and Method: The study was conducted on 50 neonates a time based prospective study. All consecutive neonates fulfilling the inclusion and exclusion criteria are subjected to sepsis screening. Results: Among risk factors PROM and fetal distress ...

background: the appropriateness of using serum levels of procalcotonin (pct) for early diagnosis of newborn sepsis is still controversial. therefore, the objective of the present study was to compare the usefulness of pct with those of serum levels of c-reactive protein (crp) and white blood cell (wbc) counts in the diagnosis and response to treatment of neonatal sepsis.   methods: a total of 4...

Neonatal mortality is increasingly recognized as an important global public health challenge that must be addressed if we are to reduce child health disparities between rich and poor countries. Most of the estimated 4 million neonatal deaths per year occur in low and middle income countries. Three conditions: infection, birth asphyxia, and consequences of premature birth/low birth weight, are r...

OBJECTIVE The purpose of this study was to compare maternal characteristics and neonatal morbidity and mortality rates that are associated with early-onset neonatal sepsis that is caused by group B Streptococcus and Escherichia coli. STUDY DESIGN This was a retrospective review of newborn infants with a positive blood culture (and/or cerebrospinal fluid) that was positive for either E coli or...

Sepsis is a major cause of neonatal mortality and morbidity worldwide. A recent report suggested that murine neonatal host defense against infection could be compromised by immunosuppressive CD71(+) erythroid splenocytes. We examined the impact of CD71(+) erythroid splenocytes on murine neonatal mortality to endotoxin challenge or polymicrobial sepsis and characterized circulating CD71(+) eryth...

The aim of this cohort (prospective) analytic study was to determine the microbiological pattern of bacterial infection in the Neonatal Intensive Care Unit of Kasr El Eini Hospital, to investigate microbial colonization of neonates at birth before any interference and to examine whether surface cultures yielded information helpful in management. The study population comprised 70 high risk neona...

The epidemiology of nosocomial infections in Turkish neonatal intensive care units (NICUs) shows that nosocomial sepsis is an important problem, especially for very low birth weight (VLBW) infants, and gram-negative agents, particularly Klebsiella species, are still the major causes of nosocomial infections. Sepsis frequency was 6.4%, ranging from 2.1 to 17%, in 16 centers in Turkey. Sepsis fre...

INTRODUCTION Neonatal mortality in developing countries is usually due to an infectious cause. The gold standard of investigation in developing countries is a positive blood culture. It is important to know the aetiology of neonatal bloodstream infections so that empiric treatment can be effective. METHODOLOGY We conducted a retrospective clinical audit over ten years between January 2000 unt...

Background: Sepsis is an important cause of neonatal morbidity and mortality. In Egypt, A multi-center study reported that 45.9% of the neonates admitted to neonatal intensive care units (NICUs) were due to suspected neonatal sepsis. Proper management is not guaranteed due to nonspecific symptoms and signs especially at the onset of disease, delay of culture results and high rate of false negat...

sareshtedari m 1 (md) , shahamat h 1 (md) , sadeghi t 2 * (msc)       1 department of pediatrics, school of medicine, qazvin university of medical sciences, qazvin, iran   2 department of pediatrics, school of nursing and midwifery, tehran university of medical sciences, tehran, iran     received: 22 jan 2011, accepted: 23 jun 2011       abstract     introduction: regarding the importance of me...