materials and methods the level of plasma il-6 and blood culture were checked in all the term neonates suspicious to sepsis admitted to the neonatal intensive care unit of shahid beheshti hospital of kashan during 2010-2011. positive blood culture was considered as definite sepsis and negative blood culture as suspicious sepsis. then, the level of il-6 was compared with the state of blood cultu...

Background Neonatal sepsis is one of the most critical illness in neonates that is responsible for a great proportion of morbidity and mortality in neonates so early diagnosis and identification of high risk cases is a challenging aim of our study. The purpose of this study was to investigate the prognostic value of red cell distribution width (RDW), in neonatal sepsis at the time of admission ...

introduction early diagnosis of neonatal sepsis is essential for successful treatment. blood culture is a gold standard for diagnosis but the final results are not available until 48-72 hours after culture. interleukin-6 (il-6) as a marker plays a critical role in the induction of c-reactive protein (crp) synthesis in the liver. it has been hypothesized that this cytokine could be detected in b...

Neonatal sepsis (NS) is one of the major causes morbidity and mortality in neonatal age. NS classified according to time symptoms Early-Onset Sepsis (EOS) Late-OnsSepsis (LOS). In new studies, neutrophil/lymphocyte ratio (NLR) platelet/lymphocyte have been used determining existence severity sepsis. This a sign inflammation, it can be foreseeing septicemia.

objective(s) in the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. in this study, we aimed to investigate the value of procalcitonin, and c- reactive protein in establishing the diagnosis of neonatal sepsis. materials and methods blood samples were collected at admission from 69 neonates with suspected infection (admitte...

Background: Early diagnosis of neonatal sepsis is quite challenging. I/T ratio (immature to mature neutrophil ratio) is a highly sensitive marker of sepsis but is time-consuming and subjective. Off late, volume conductivity and scatter (VCS) of neutrophils are among the newer parameters available for screening a septic neonate. This study aimed to determine the correlation between the I/T ratio...

neonatal sepsis, a life-threatening condition, presents with non-specific clinical manifestations and needs immediate empirical antimicrobial therapy. choosing an appropriate antibiotic regimen covering the most probable pathogens is an important issue. in this study we compared the effectiveness of ceftizoxime and amikacin in the treatment of neonatal sepsis both in combination with ampicillin...