Adult adrenal cortex is a differentiated endocrine tissue that undergoes permanent regeneration. Proliferation of the progenitor cells is restricted to the outer quarter of the cortex (Zajicek et al. 1986, Mc Nicol & Duffy 1987). After this initial proliferative step, adrenocytes are displaced centripetally, until they reach the junction to the medulla (the whole process takes about 100 days in...

Although the role of arachidonic acid (AA) in angiotensin II (ANG II)- and potassium-stimulated steroid production in zona glomerulosa cells is well documented, the mechanism responsible for AA release is not fully described. In this study we evaluated the mechanism involved in the release of intramitochondrial AA and its role in the regulation of aldosterone synthesis by ANG II in glomerulosa ...

Expression of the diverse subtypes of inositol 1,4,5-trisphosphate (InsP3) receptor (IP3R) was examined in rat adrenal glomerulosa cells. The polymerase chain reaction products were characterized by means of DNA sequencing and/or restriction enzyme mapping. The predominant subtype expressed is IP3R-1; its alternatively spliced variants containing and lacking segment S1 are present in comparable...

nepeta depauperata belongs to the lamiaceae family and is one the persian endemic plants which has not been investigated biologically. in the present paper we had focused on the assessment of the antibacterial and antifungal activities of the total methanolic extract and different sub-fraction of the flowering aerial parts of it. the antibacterial and antifungal activities were investigated by ...

Wild animal hunters and photographers have long taken advantage of the attraction that catnip holds over members of the cat family, while domestic cat owners purchase dried catnip leaves for use as a rejuvenator and exerciser that will bring old cats to new life. Indeed, when cats have the leaves placed near them, they immediately approach, sniff, and shortly thereafter rub their faces into the...

Numerous spironolactone bodies have been detected in the zona glomerulosa cells of the adrenal cortex of a 36-year-old spironolactone-treated woman whose non-tumorous right adrenal gland was removed surgically because of primary hyperaldosteronism. Electron microscopy revealed spherical laminated whorls which consisted of a central core composed of an amorphous electron-dense material surrounde...