abstract          background and objectives: concentration low-density lipoprotein (ldl) is one of the strongest indicators of atherosclerosis and predicts the diagnosis of cardiovascular diseases. ldl measurement accuracy is very important. ldl can be measured directly, such as enzymatic and nephelometry methods or can be calculated using friedewald's formula. despite the development of e...

BACKGROUND The measurement of C-reactive protein (CRP) concentrations has been of interest as a classical marker of acute phase response; in addition, it has been of particular interest in cardiovascular risk stratification where high-sensitive measurements are necessary. Since CRP is able to bind phospholipids (mainly phosphocholine) in the presence of calcium ions, we explored the possibiliti...

A multicenter study conducted in healthy population of 6 cities from the 4 corners and central China for 7 serum-specific proteins to identify the sources of variation and establish the reference intervals on 2 automation platforms.A total of 3148 subjects aged 19 to 64 years old were enrolled in this study to ensure at least 120 participants in each 10-year age group and each city. The majorit...

BACKGROUND Variation of normal immunoglobulin (Ig) levels between different genetic and environment factors has been studied. Although antibody deficiency diseases can start from infancy, data of Ig reference levels in children aged ≤24 months are still limited, especially in Asian children. PURPOSE The aim of this study was to determine serum IgG, IgA, IgM, and IgG subclasses in healthy Thai...

BACKGROUND Stability of circulating high-sensitivity C-reactive protein (hsCRP) concentrations has implications for its utility in assessing cardiovascular disease (CVD) risk. We sought to determine hsCRP reproducibility in an indigenous Australian cohort with a view to use hsCRP as a marker of future CVD in community-based risk-factor screenings. METHODS Seventy people living in a community ...

Fine particle sulfate was measured continuously for 90 consecutive days, from August through October 1999, at Big Bend National Park. Measurements were made with a prototype integrated collection and vaporization cell, whereby particles are humidified and collected by impaction onto a metal strip and analyzed in place by flash-vaporization and pulsed fluorescence detection of the evolved sulfur...