OBJECTIVES Many patients present with bilateral stones. There is a unique group of patients, however, that presents with stones exclusively on one side. We hypothesize that in such situations, 24-hour urine collections may not reveal specific defects on the affected stone-bearing kidney. We therefore evaluated selective 12-hour urine collections after percutaneous nephrolithotomy (PNL) to help ...

Background It is well established that nutritional habits are relevant in the prevention of Idiopathic Calcium Nephrolithiasis (ICN) and the Mediterranean diet is believed to be protective against nephrolithiasis and not only against cardiovascular events. A case-control study was performed to establish the nutritional habits of Italian ICN patients and the nutritional determinants of lithogeni...

a. We recommend that unenhanced computed tomography is the preferred imaging modality for the diagnosis of suspected nephrolithiasis in autosomal dominant polycystic kidney disease (1B). b. We recommend that patients with autosomaldominant polycystic kidney disease complicated by nephrolithiasis should be investigated for predisposing urinary metabolic abnormalities (1C) and we suggest receive ...

PURPOSE To study whether -160 C > A (rs16260) and -347 G > GA (rs5030625) single nucleotide polymorphisms of the regulatory region (rSNPs) of CDH1 gene modulate the risk of nephrolithiasis. METHODS Genomic DNA of 101 patients with calcium oxalate nephrolithiasis and 114 healthy controls were screened for both polymorphisms, using polymerase chain reaction-restriction fragments length polymorp...

The association between nephrolithiasis and acromegaly has been previously described. Although the mechanism has been established, the urological literature sparsely discusses clinically suspecting that patients with recurrent nephrolithiasis could have acromegaly and subsequently referring them for accurate diagnosis and treatment. We present a case of occult acromegaly secondary to a pituitar...

Introduction: Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract. Biologic drugs target specific molecules in body’s immune system to control inflammation. Recent studies have suggested potential link between their use and an increased risk nephrolithiasis. We conducted study further investigate this association. Methods: The used multiple logistic regre...

background nephrolithiasis is a widespread multifactorial disorder. constitutional, environmental and genetic factors play a role in stone formation. although important advances have been made in understanding the pathophysiology of stone formation, none of the many theories have given a satisfactory explanation of this process. objectives the objective of study was to evaluate the probable rel...

Background Pediatric nephrolithiasis is a condition the prevalence of which varies geographically with multiple etiologies. The aim of this study was to determine possible concomitant anatomic and metabolic disturbances in children with nephrolithiasis and to answer the questions regarding the role of each metabolic and anatomic abnormality. Materials and Methods Between 2007 and 2015, 1,080 pa...