We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-year-old man with a 5-year history of IgA nephropathy developed Vogt-Koyanagi-Harada syndrome. At the time of the eye disease presentation, Ig...

henoch-schönlein purpura nephritis and iga nephropathy are currently considered to be different clinical presentations of the same disease. there is need for a reliable proven, morphologic classification that can help clinicians more accurately formulate treatment strategies for patients with henoch-schönlein purpura nephritis. considering that henoch-schönlein purpura nephritis and iga nephrop...

abstract pseudoxanthoma elasticum is a rare, hereditary, multisystemic disease affecting the skin, eye, and cardiovascular system. renal involvement is uncommon. we describe two cases of pseudoxanthoma elasticum (pxe) in two women with distinctive skin lesions and nephrocalcinosis that renal ultrasonography showed a characteristic pattern of dotted increased echogenicity in the corticomedullary...

objective(s) oxidative stress plays an important role in diabetic nephropathy pathogenesis. rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. material and methods forty male rats were uninephrectomized from the left flank.the rats were divided in four groups randomly; group one as control, group two diabetic untreatment, g...

background: angiotensin i converting enzyme (ace) is a zinc metalloproteinase, converts ang-i to ang- ii, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. objective: to investigate the relationship between ace i/d polymorphism and type 2 diabetes in 261 iranian casecontrol pairs. methods: 170 patients (85 type 2 diabetics with nephropathy a...

background: diabetic nephropathy is considered to be the most common cause of end stage renal disease (esrd). proteinuria is declared as the most marked risk factor in progression towards esrd. the aim of this study was to evaluate the efficacy of pentoxifylline for reduction of proteinuria in type ii diabetic patients. methods: from may 2007 to june 2008, this randomized clinical trial study w...

background: the role of attenuation in antioxidant capacity or expansion of pro-oxidant/oxidant is well known for the development of stress oxidative. the aim of this study was to evaluate the plasma antioxidant capacity along with uric acid in patients with diabetic nephropathy (dn+) and without diabetic nephropathy (dn-). materials and methods: the research population included 88 patients wit...

background: diabetes mellitus is a metabolic disorder and its subsequent complications such as retinopathy, nephropathy, ulcers,disability, and amputation increase the burden of the disease. patient knowledge-improving programs are employed to prevent disease progression and to improve the quality of life of the patients. in this way, we need to characterize the groups of patients in urgent nee...

normal 0 false false false en-us x-none ar-sa background: nowadays vitamin d deficiency is a notable medical condition world-wide and also in iran. since, vitamin d can have reoprotective effect by inhibiting the renin-angiotensin system; it appears that low vitamin d level can worsen the renal injury in diabetic patients. this study demonstrates the effect of vitamin d 3 therapy on reducing pr...

objective: diabetic nephropathy is a major diabetes complication. arterial resistance index (ri) may predict deterioration in kidney function. this study was designed to compare renal arterial ri in different stages of renal function according to glomerular filtration rate (gfr), serum creatinine level and proteinuria. materials and methods: in a cross-sectional study on 81 diabetic patients in...