background: many people suffer from nerve injury. the time consuming nature of the treatments makes the condition worse. therefore, finding a way to accelerate the process of nerve repair is very important. objective: to determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration. methods: the experimental model included crushed rat’s sciatic nerve. 40 rats w...

a common cause of peripheral nerve injury is trauma. the positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. in this experiment, the effect of intraperitoneal administration of ubiquinone (coq10) on an acute experimentally sciatic nerve crush was studied in a rat model. forty-five male wistar rats, weighing between 160-180 g were u...

the purpose of this experimental study was to evaluate the effect of chicken amniotic fluid (af) on a cross section of rat sciatic nerves. thirty adult male sprague-dawley rats weighing 275 to 300 g, were randomized into three groups treated with (1) amniotic fluid or af (n=10), (2) normal saline or ns (n=10), and (3) sham surgery (n=10). the af was aspirated from the amniotic cavity of incubat...

despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat sciatic nerve gap. fifty- four male wistar rats were divided into three experimental groups (n = 18),...

Autograft is gold standard treatment for peripheral nerve repair up to now. Eggshell membrane (ESM) as nerve guide channel effectively enhances nerve regeneration. Dimethyl sulphoxide (DMSO) has anti-inflammatory and anti-oxidant properties. The aim of this study was to evaluate the effect of DMSO+eggshell membrane guide channel on sciatic nerve regeneration in rats. Thirty two adult male rats ...

a b s t r a c tintroduction: peripheral nerve injury is a common disorder and leads to permanent neurological defects. schwann cells have been shown to have nerve repair after being transplanted in peripheral nerve injury. the aim of this study was to determine the beneficial effect of allograft schwann cells on electrophysiological outcome after transection of the sciatic nerve in rats.methods...

objective: to assess the effect of combination of pulsed electromagnetic fields (pemf) with predatory stress on transected sciatic nerve regeneration in rats.  methods: in sham- operated group (sog) the nerve was manipulated and left intact. the 10-mm rat sciatic nerve gap was created in rats. in transected group (transected) nerve stumps were sutured to adjacent muscle and in vein graft group ...

the effect of nerve growth factor (ngf) on regeneration of rat sciatic nerves in adult rat was studied. the sciatic nerve was cut out across a 6‑mm gap, then the proximal and distal stumps were inserted into the silicone tube chamber. 7s ngf was extracted from submaxillary gland and then was injected into the silicone in experimental group. after seven months nerve was transected and stained wi...