cell replacement therapy has provided the basis for future clinical applications to treat central nervous system injuries fallowing by car accidents. induced functional neurons are an option for replacing the lost neurons. the ability to monitor changes in membrane potential is a useful tool for studying neuronal function, but there are only limited options available at present. here, investiga...

background: occupational lead poisoning is a health problem in iran. it has not previously been studied in traditional tile makers. objective: to determine the prevalence of lead poisoning and its complications in traditional tile workers in mashhad, northwest of iran. methods: we visited workers in two traditional tile factories and collected data by direct history taking and physical examinat...

background: many studies have been done in order to interpret correctly the results of ethanol analysis and its related problems. unfortunately, it was not easy to determine bac rate, due to postmortem different conditions or personal and clinical differences in metabolism and excretion of ethanol. the time between death and autopsy, the environmental conditions (temperature and humidity) are i...

In this investigation the effects of excess vitamin A administration during the early embryonic period were studied. Intramuscular injection of a single dose of 15000,20000 or 25000 IU/kg vitamin A to pregnant Balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (CNS) including exencephaly, h...

background : primary central nervous system involvement and central nervous system relapse are poor prognostic events in acute lymphoblastic leukemia. due to severe skeletal and endocrine complications of craniospinal radiotherapy, only cranial radiotherapy is advisable. however only 15% of the cases with central nervous system relapse may remain in remission; a second central nervous system or...

silver nanoparticles (agnps) have gained considerable interests during the last decade due to their excellent antimicrobial activities. despite their extensive use, the potential toxicity of these nanoparticles and possible mechanisms by which they may induce adverse reactions have not received sufficient attention and no specific biomarker exist to describe and quantify their toxic effects. na...

nigella sativa (ns) (ranunculaceae family) is generally utilized as a therapeutic plant all over the world. the seeds of the plant have a long history of use in different frameworks of medicines and food. in islamic literature, it is considered as one of the greatest forms of therapeutics. it has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicit...

allergic rhinitis is a chronic respiratory disease. sympathetic hypofunction is identified in all of the allergic rhinitis patients. moreover, allergic rhinitis is associated with decreased peak nasal inspiratory flow (pnif) and impaired lung functions. the aim of this study was to investigate effects of six-week of aquatic exercise on the autonomic nervous system function, pnif and lung functi...