sebaceous carcinoma is a relatively rare cutaneous tumor that is most commonly derived from the sebaceous glands located in periorbital area. the extraocular occurrence of this tumor is very rare. we report a case of an 85 years old woman who presented with a slowly enlarging mass on the right temporal region. histological examination of the lesion revealed a malignant sebaceous carcinoma occur...

Nevus comedonicus is an uncommon skin abnormality characterized by an aggregation of dilated follicular orifices filled with keratinous material. Nevus comedonicus is occasionally complicated with other conditions including cataracts, skeletal defects, central nervous system abnormalities or other extra-cutaneous diseases (nevus comedonicus syndrome). Although most cases of nevus comedonicus oc...

The purpose of this study was the clinical and histo-immunohistochemical analysis of two cases: a cutaneous pigmented facial malignant melanoma and a lumbar congenital nevus with malignant transformation. A series of clinical elements raised the suspicion of some malignant melanocytic lesions and the histopathological analysis through the paraffin embedding technique confirmed the clinical susp...

A high number of nevi is the most significant phenotypic risk factor for melanoma and is in part genetically determined. The number of nevi decreases from middle age onward but this senescence can be delayed in patients with melanoma. We investigated the effects of nevus number count on sentinel node status and melanoma survival in a large cohort of melanoma cases. Out of 2,184 melanoma cases, ...

Inflammatory linear verrucous epidermal nevus is a variant of verrucous epidermal nevus, characterized by recurrent inflammatory phenomena. Despite well-established clinical manifestations, the differential diagnosis between inflammatory linear verrucous epidermal nevus and linear psoriasis remains difficult. Clinical history, physical examination and histopathology analysis may not be sufficie...

Linear Nevus Sebaceous Syndrome (LNSS) is a rare sporadic oculoneurocutaneous disorder, also classified as Organoid Nevus Syndrome. It consists of a triad of midline facial linear nevus sebaceous, central nervous system and ocular abnormalities. To the best of authors' knowledge ophthalmic features of LNSS have never been reported in Pakistani population. We report two cases of LNSS, associated...

background spitz nevus is an infrequent acquired melanocytic nevus. there is still a challenge for dermatopathologists in distinguishing spitz nevus from malignant melanoma particularly in adults since there is no immunohistochemistry or molecular markers which differentiate spitz nevus from melanoma. objectives the aim of this study is to make clear what clinico-histopathological features of s...

Becker's nevus, also called Becker's melanosis or pigmented hairy epidermal nevus, is a benign cutaneous hamartoma characterized by hyperpigmented macule usually with hypertrichosis. It is rarely associated with neurofibromatosis. We report a 2 1⁄2 yrs old male child with coexistent congenital Becker’s nevus and type 1 neurofibromatosis.

Nevus is a group of melanocytes that grow together to form benign growth on the skin. It often black lesion may protrude from Becker's nevus hyperpigmented presents congenitally or acquired. The pigmentation and unusually high hair might darker with time. nevus, which can interchangeably be called melanosis, rare disease usually presented by men. following case 21-year-old male who his right ar...