OBJECTIVE Mandated state newborn screening programs for the approximately 4 million infants born each year in the United States involves the following 5 components: 1) initial screening, 2) immediate follow-up testing of the screen-positive newborn, 3) diagnosis confirmation (true positive versus false positive), 4) immediate and long-term care, and 5) evaluation of all of the components of the...

T here are many ethical questions concerning research on preterm and newborn infants, why much has to be done on animals. Therefore, research has been, and is continuously done, on newborn lambs, monkeys, pigs, mice, and rats. During the last decades, the use of ‘‘piglets’’ as research animals has become more and more usual. But, what is a piglet, or actually what or who is a piglet? Doing a se...

certain strains of staphylococcus aureus produce a toxin which cause epidermal exfoliation within 18 hours after direct subcutaneous or intraperitoneal injection into newborn mice. the extracellular product responsible for exfoliation is termed exfoliative toxin (et). in the present studies a modified assay system has been developed for detection of exfoliativeactivity in toxin negative strains...

the interpretation of supernumerary chromosome is important for genetic counseling and prognosis. here, we used snp array and conventional karyotyping method to identify a denovo marker chromosome originated from chromosome 22 and 11 in a newborn transferred to the neonatal intensive care unit of shahid sadoughi hospital in 2015.  clinical abnormalities identified in the newborn were dysmorphic...

to evaluate the changes of abr values in hyperbilirubinemic newborns, 85 cases with severe jaundice (total bilirubin levels over 16 mg/dl and direct bilirubin less than 2 mg/dl) were selected from those admitted to children's medical center by simple sampling method. these infants had no other problem except jaundice. abr was taken before treatment in all cases and in some (10 cases) after...

apparent life-threatening event (alte) is a major cause of neonatal emergency visits. in this paper, we presented the case of a three-day-old neonate with multiple indications of alte. the patient was referred to the emergency department due to a cyanotic attack before admission. the neonate woke a few hours after breastfeeding and turned blue while crying, which was resolved spontaneously with...

introduction: apgar score evaluation is a common method to evaluate physiological changes of newborns and can help to predict the neonatal life chance. this study was conducted to determine the apgar score of newborns with two methods of vaginal delivery and spinal anesthesia and its relationship with the associated factors in gorgan health care facility. materials and methods: a cross-sectiona...

introduction: screening of newborns with seizure, who have curable pathologic brain findings, might be able to improve their final outcome by accelerating treatment intervention. the present study aimed to evaluate the brain ultrasonography findings of newborns hospitalized with complaint of seizure. methods: the present cross-sectional study designed to evaluate brain ultrasonography findings ...

an eleven-day boy neonate with a fetal anamnesis of grade 1 bilateral hydronephrosis according to the grading of the society for fetal urology (sfu), came to our attention for an acute osteoarthritis secondary to urosepsis. in the urological follow-up, a severe bilateral vesico-ureteral reflux (vur) was diagnosed. an early post-natal, reno-vesicle ultrasound evaluation could have changed the cl...

background: the aim of the study was to evaluate the third trimester urinary iodine excretion and to assess its relation with newborns thyroid function. materials and methods: a total  of  208 healthy third trimester pregnant women without previous history of thyroid disease were included in the study. urinary iodine levels of mothers were measured and neonatal tsh levels were screened on the 3...