Nigella sativa, commonly known as black seed possess an extensive pharmacological potential and has emerged a wonder herb with rich historical religious background. For decades, people all over the world have utilised N. sativa seeds oil to treat wide range of illnesses. Because was stated cure for every illness except death in one Prophetic hadiths, it is regarded by Muslims greatest forms cur...

introduction: some studies have demonstrated the potential of herbal drugs for the treatment of various diseases associated with impaired vascular nitric oxide (no). for diagnosis of the mechanism of these herbal plants, it seems necessary to evaluate the herbal extracts on the endothelium cell. the aim of the study was to investigate the effect of extract of trigonella foenum-graecum (t.foenum...

Nigella sativa Linn. (Family-Ranunculaceae) is a widely used medicinal plant throughout India and popular in various Indigenous System of Medicine like Ayurveda, Siddha, Unani and Tibb. The seeds are used as astringent, bitter, stimulant, diuretic, emmenagogue and anthelmintic. They are also useful in jaundice, intermittent fever, dyspepsia, paralysis, piles and skin diseases. The present revie...

Objective: Oxidative stress plays an important role in the etiology of diabetic complications. Diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. Materials and Methods: Diabetes induced by 60 mg/kg STZ, i....

Nigella sativa has been used as traditional medicine for centuries. The crude oil and thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc. It is effective against cancer in blood system, lung, kidney, liver, prostate, breast, cervix, skin with much safety. The molecular mechanisms ...

Sinusitis is associated with inflammation and infections of air-filled cavities of sinuses. The aim of this study was to evaluate the potential efficacy of Nigella sativa seed fixed oil in management of sinusitis. The information was extracted from accessible international databases, traditional books, electronic resources, and unpublished data. Results The results of investigations on N. sat...

Hexane extract of the seeds of Nigella sativa L. prevented pregnancy in Sprague-Dawley rats treated orally at 2 g/kg daily dose on days 1-10 post-coitum. Significant antifertility activity was also observed in its column fractions and subfractions. At contraceptive dose, the active hexane extract exhibited only mild uterotrophic activity comparable almost to 0.002 mg/kg dose of 17 varies; is di...

Nigella sativa seeds have wide therapeutic effects and have been reported to have significant effects against many ailments such as skin diseases, jaundice, gastrointestinal problems, anorexia, conjunctivitis, dyspepsia, rheumatism, diabetes, hypertension, intrinsic hemorrhage, paralysis, amenorrhea, anorexia, asthma, cough, bronchitis, headache, fever, influenza and eczema. Thymoquinone (TQ) i...