Introduction: Amphotericin B is considered as one of the most effective antifungal drugs presently used to treat systemic fungal infections; however, nephrotoxicity remains the major side effect. The current study is therefore, designed to determine Amphotericin B induced nephrotoxicity and its prevention by administration of Nigella sativa (NS) extract in albino mice. Materials and Methods: Th...

Background: The seeds of Nigella sativa plant have been used to promote health and fight disease for centuries especially in the Middle East and Southeast Asia. This plant has been a great focus of research. This clinical study was undertaken to determine the adjuvant effect of Nigella sativa oil on various clinical and biochemical parameters of the metabolic syndrome. Methodology: This prospec...

BACKGROUND Vitiligo is one of the autoimmune skin diseases that destroy the melanocytes of the skin. Moreover, its prevalence varies in different countries and regions. OBJECTIVES The aim of this study was to compare the effect of Nigella sativa and fish oil on vitiligo lesions of the patients referred to a dermatology clinic. MATERIALS AND METHODS This randomized, double blind clinical tri...

Nigella sativa L. (Ranunculaceae) seeds (black cumin) that contain high oil, terpene, protein, alkaloids are an economically important for medicine and food industry. Lack of an efficient DNA isolation procedure is a limiting factor for any molecular studies of these plant. We have used a genomic DNA isolation protocol for Nigella sativa seeds based on a hexadecyltrimethylammonium bromide (CTAB...

The present study was designed to investigate some histopathological changes produced by cimetidine on male reproductive organs (testes & epididymis) in mice and extended to examine wherethere using of aqueous suspension of powdered Nigella sativa seeds have ability to reduce this toxicity.Forty male mice were divided into 4 groups. The first group received 25 mg/kg B.W. of cimetidine orally on...

results there was a statistically significant difference in vaginal itching, discharge, irritation, vulvovaginal redness and inflammation after the treatment between the two groups and much more in the study group (p ˂ 0.001). however, the culture and wet mount (with koh) results showed much improvement in the study group after treatment. conclusions the use of nigella sativa l. capsule with cl...