An immunosuppressive variant of Friend murine leukemia virus (F-MuLV), FIS-2, induces suppression of the primary antibody response against sheep erythrocytes (SRBC) in adult NMRI mice more efficiently than the prototype F-MuLV clone 57 (cl.57). It is, however, less potent than F-MuLV cl.57 in inducing erythroleukemia upon inoculation into newborn NMRI mice. Nucleotide sequence analysis shows a ...

The highly mutagenic heterocyclic amines, 2-amino-3-methylimidazo[4,5-nquinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MelQ), are formed during heating of pro tein-rich foods. In order to gain information about the distribution and fate of IQ and MelQ in vivo, a whole-body autoradiographic study of i.v.-injected 14C-labeled IQ and MelQ has been per formed in male NMRI, pregnant ...

Background : Previous studies have demonstrated that Dexamethasone, a widely used GC, induces apoptosis in testis by decreasing the testosterone levels. Galectin-3 (Gal-3), a member of the ß-galactoside-binding lectins, plays critical roles in diverse biological events including cell growth, apoptosis, cell adhesion and immunomodulation. In this study, the effects of Dexamethasone (Dex) on gale...

The high-field permanent magnetic circuits of 1.2 T and 1.5 T with novel magnetic focusing and curved-surface correction are developed. The permanent magnetic circuit comprises a magnetic yoke, main magnetic steel, nonspherical curved-surface magnetic poles, plugging magnetic steel, and side magnetic steel. In this work, a novel shimming method is proposed for the effective correction of base m...

Introduction: Hydatid cyst is among parasitic diseases common between man and domestic animals, as well as domestic and non domestic carnivorous animals. This disease causes organ damage and injuries in human, and sometimes leads to death. This study aims at assessment of secondary hydatid cyst growth in laboratory animals and determination of their sensitivity. Materials and Methods: The Pr...

In the present study, the effects of pregnant NMRI mice restraint stress on the responsibility of their children to the behavioral properties of morphine, sulpiride and dextromethorphan were investigated in the F2 generation. Twenty four pregnant NMRI female mice (W: 25 g) were divided into the experimental and control groups (n = 12/group). Animals in the experimental group were kept in the r...

background: galectin-3 (gal-3), a β-galactoside-binding lectin, is a multifunctional lectin that involves in a number of critical biological processes. objective: the purpose of this study was to investigate the expression pattern of gal-3 in mouse endometrium during estrus phase of estrous cycle and pre-implantation. materials and methods: in this experimental study 42 nmri female mice were di...

Background: It is assumed that adult stem/progenitor cells are responsible for cycling remodeling of the uterus endometrium throughout the reproductive life of the female. This study aimed to identify and localize stem/progenitor cells in the mice uterus using immunohistochemistry. Materials and Methods: 6-8 weeks old virgin female NMRI mice were submitted to the vaginal smear examination to de...