Background and Aim: Non-Alcoholic Fatty Liver Disease (NAFLD) is the major cause of chronic liver disease in developed countries. In this study, we identified the most important transcription factors and biological mechanisms affecting the incidence of fatty liver disease using the promoter region data mining. Materials and Methods In this study, at first, the marker genes associated with this...

Background and Objective: Non-alcoholic fatty liver disease is the most common hepatic disorder in industrial societies with a prevalence ranging within 15-35% in the European and Middle Eastern populations. This disease is one of the most important causes of mortality due to hepatic diseases. Regarding this, the aim of the present study was to investigate the effect of a six-week combined aero...

Abstract Background and Objectives Non-alcoholic liver disease (NAFLD) is a spectrum of diseases, ranging from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH) which can lead to liver cirrhosis and hepatocellular carcinoma. Nonalchololic fatty liver  is the most prevalent hepatic disorder worldwide which can affect up to the one out of four adults. Little is known about...

Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease is increasing in adults and children worldwide. Obesity, insulin resistance or diabetes type II, hyperlipidemia and hypertriglyceridemia plays a major role in the epidemiology of this disease. Cytokeratin 18 (CK-18) the major intermediate filament protein in the liver is a marker of increased hepatocyte apoptosis. ...

Background & Objectives: Non-alcoholic fatty liver disease, characterized by the deposition of fat in liver cells, can cause fibrosis, cirrhosis, and liver cell damage if not controlled. The aim of this study is to compare the effects of medication therapy and exercise training with diet on liver enzyme levels and liver sonography in patients with non-alcoholic fatty liver disease (NAFLD). Mate...