background non-alcoholic fatty liver disease (nafld) is the most common form of liver disease in many parts of the world. objectives the aim of the present study was to identify the most important factors influencing nafld using a classification tree (ct) to predict the probability of nafld. patients and methods this cross-sectional study was conducted in kavar, a town in the south of fars prov...

background: a hypothesis has been presented about the role of serum iron, ferritin and transferrin saturation among patients with non-alcoholic fatty liver disease (nafld) and resistance to insulin (metabolic syndrome [mets]), but there is much controversy. this study aimed at investigating the level of serum iron and demographic characteristics in patients with nafld with or without mets. meth...

Non-alcoholic fatty liver disease (NAFLD) is a form of clinical syndrome characterized by the fatty degeneration in liver histology and should be further investigated. The aim of the study was to investigate the effects of blood glucose, serum chemerin and insulin resistance on non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus to provide a basis for the prevent...

Background and Aims : It is now well established that non-alcoholic fatty liver disease (NAFLD) associated with a significant increase in the risk of adverse cardiovascular events. NAFLD-specific scores, considering traditional nontraditional factors, are needed to improve patient care. Liver fibrosis may be an integrative indicator burden cardiometabolic factors. also represent subclinical ath...

Background and Aims:Patatin-like phospholipase domain protein 3 (PNPLA3) polymorphisms (rs738409 C>G) are associated with non-alcoholic fatty liver disease (NAFLD). We performed a systematic review and meta-analysis to examine the association of PNPLA3 polymorphisms with the spectrum and severity of this disease. Methods: Studies evaluating the association between the PNPLA3 polymorphism spectr...

Non-alcoholic fatty liver disease (NAFLD) includes a cluster of liver disorders ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH) and cirrhosis. Due to its liver and vascular complications, NAFLD has become a public health problem with high morbidity and mortality. The pathogenesis of NAFLD is considered a "multi-hit hypothesis" that involves lipotoxicity, oxidative stress...

As the number of individuals with non-alcoholic fatty liver disease (NAFLD) has increased, the influence of NAFLD on other metabolic diseases has been highlighted. Accumulating epidemiologic evidence indicates that NAFLD not only affects the liver but also increases the risk of extra-hepatic diseases such as type 2 diabetes mellitus, metabolic syndrome, dyslipidemia, hypertension, cardiovascula...

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic disease, with a prevalence that increasing in parallel global rise obesity and type 2 diabetes mellitus. The pathogenesis NAFLD complex multifactorial, involving environmental, genetic metabolic factors. role diet gut microbiome gaining interest as significant factor pathogenesis. Dietary factors induce alterations compos...