The rapidly increasing prevalence of childhood obesity and its associated co-morbidities such as hypertriglyceridemia, hyper-insulinemia, hypertension, early atherosclerosis, metabolic syndrome, and non-alcoholic fatty liver disease are major public health concerns in many countries. Therefore the trends in child and adolescent obesity should be closely monitored over time, as in the near futur...

The former is a sequel of acute viral hepatitis A and B, toxic hepatitis as a result of severe poisoning with hazardous substances or rapid blockage of the liver blood supply, while the latter one is an after-effect of chronic hepatitis B, C and autoimmune hepatitis, longterm alcohol abuse, disordered bile outflow, certain drugs administration, non-alcoholic fatty liver disease (NAFLD) and non-...

PETACH TIKVA, Israel, May 3, 2017 /PRNewswire/ -Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE: CFBI), a biotechnology company with a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today provided an update on a Phase II clinical trial to evaluate its liver drug candidate Namodenoson (CF102) in the treatment of non-alcoholic fatty liver disease...

AIM To investigate the natural history of patients with non-alcoholic steatohepatitis by means of a prospective histological study. METHODS One thousand five hundred and seventy one patients underwent liver biopsy at the Western Infirmary in Glasgow during the 10 year period 1985 to 1994. All biopsies were reported by a single pathologist: 62 were confirmed as having non-alcoholic steatohepat...

the epidemic of obesity and associated features of metabolic syndrome including NASH (non-alcoholic steatohepatitis) and NAFld (non-alcoholic fatty liver disease) is spreading worldwide; thanks to the increasingly sedentary life style! it is estimated that 12-15% of the global population is affected with NAFld; 50% of diabetics develop NAFld. it is seen in 57-74% of obese persons and the preval...

The retrospective analysis of 378 medical records inpatients with steatohepatitis (SH) depending on its etiology was performed to identify and study the type anaemic conditions (AC). Among patients SH mixed (including alcoholic) anaemia found in 32.2% cases, alcoholic (ASH) - 36.3%, non-alcoholic (NASH) 22.0 % cases. Macrocytic, hyperchromic prevailed all groups: 47.9%, ASH 56.8%, NASH 71.4%. N...

In previous studies, the relationship between aspartate aminotransferase to alanine aminotransferase ratio(AST/ALT ratio) and liver disease has been evaluated. In viral hepatitis, alcoholic liver disease and primary biliary cirrhosis, AST/ALT ratio has been proven to be an indicator of liver cirrhosis.1-3 AST/ALT ratio was a potential value in differentiating nonalcoholic steatohepatitis from a...