This paper aims at investigating the problem of fast convergence to Nash equilibrium (NE) for N-Player noncooperative differential games. The proposed method is such that players attain their NE point without steady-state oscillation (SSO) by measuring only payoff values with no information about functions, model and also actions other are not required players. based on an extremum seeking (ES)...

Background & Objective: The aim of this present study was to assess the relationship between serum zinc levels and liver histopathological findings in non-alcoholic steatohepatitis (NASH) patients.Methods: This case-control study was performed in consecutively selected NASH patients who had been referred to a general hospital. The control group consisted ...

Pareto-optimal Nash equilibrium is a refinement of the Nash equilibrium. An evolutionary method is described in order to detect this equilibrium. Generative relations induces a non-domination concept which is essentially in the detection method. Numerical experiments with games having multiple Nash equilibria are presented. The evolutionary method detects correctly the Pareto-optimal Nash equil...

Nash [13] introduced the concept of Nash equilibria in non-cooperative games and proved that any game possesses at least one such equilibrium. A well-known algorithm for computing a Nash equilibrium of a 2-player game is the Lemke-Howson algorithm [11], however it has exponential worst-case running time in the number of available pure strategies [15]. Recently, Daskalakis et al [4] showed that ...

AIM To identify a panel of biomarkers that can distinguish between non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and explore molecular mechanism involved in the process of developing NASH from NAFLD. METHODS Biomarkers may differ during stages of NAFLD. Urine and blood were obtained from non-diabetic subjects with NAFLD and steatosis, with normal liver fu...

Consider the N -person non-cooperative game in which each player’s cost function and the opponents’ strategies are uncertain. For such an incomplete information game, the new solution concept called a robust Nash equilibrium has attracted much attention over the past several years. The robust Nash equilibrium results from each player’s decision-making based on the robust optimization policy. In...

With the prevalence of hepatitis C virus expected to decline, the proportion of hepatocellular carcinoma (HCC) related to non-alcoholic steatohepatitis (NASH) is anticipated to increase exponentially due to the growing epidemic of obesity and diabetes. The annual incidence rate of developing HCC in patients with NASH-related cirrhosis is not clearly understood with rates ranging from 2.6%-12.8%...

BACKGROUND Patients with biopsy-proven NASH and especially those with fibrosis are at risk for progressive liver disease, emphasizing the clinical importance of developing non-invasive biomarkers for NASH and NASH-related fibrosis. AIM This study examines the performance of a new biomarker panel for NASH and NASH-related fibrosis with a combination of clinical and laboratory variables. METH...

AIM To examine if liver transplant recipients with high-risk non-alcoholic steatohepatitis (NASH) are at increased risk for pre-transplant portal venous thrombosis. METHODS Data on all liver transplants in the United States from February 2002 through September 2014 were analyzed. Recipients were sorted into three distinct groups: High-risk (age > 60, body mass index > 30 kg/m2, hypertension a...

Oxidative stress is one of the key mechanisms responsible for liver damage and disease progression in non-alcoholic steatohepatitis (NASH). Antioxidants try to combat the oxidative stress and minimise the oxidative stress. In this study, the comparative effect of pioglitazone, quercetin and hydroxy citric acid on lipid peroxidation and antioxidants in experimentally induced NASH has been studie...