ISSN:0975-1459 Oxidative stress plays an important role in the pathogenesis of some diseases such as lung cancer, chronic obstructive pulmonary disease, and atheroscleorosis. Smoking may enhance oxidative stress not only through the production of reactive oxygen radicals in smoke but also through weakening of the antioxidant defense systems. Cigarette smoke may promote atherogenesis by producin...

Free radicals have been implicated in the pathogenesis of neonatal septicemia. The present study was planned to estimate the lipid peroxidation and antioxidant status in neonatal septicemia. The study was done to evaluate the lipid peroxidation and antioxidant status, both enzymatic and non-enzymatic in neonates with septicemia. This prospective study included 44 septicemic babies as cases and ...

Physical activity is well known to induce free radicals and reactive oxygen species (ROS). There are enzymatic and non-enzymatic defense systems against ROS in aerobic organisms. The aim of this study was to investigate the acute effect of eccentric and concentric training on activities of the antioxidant enzymes in physical education student's blood samples. Twenty four females students volunt...

The aim of this study was to evaluate the non-enzymatic and enzymatic antioxidant response fifteen Hypericum perforatum L. dark-grown (HR1 A-HR1 O) photoperiod-exposed (HR2 A-HR2 hairy root clones. Dark-grown HR1 clones were characterized with high biomass accumulation up-regulated phenylpropanoid metabolism through phenylalanine ammonia lyase (PAL)-mediated production flavonoids, flavan-3-ols ...

This work evaluated the enzymatic and non-enzymatic antioxidant defense systems of avocados cv. Hass stored at 7 ± 0.5 °C for 10, 20, 30 d, stage edible ripeness. The enzyme system included superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), was composed total phenolic compounds (TPC), carotenoids (TC), α-, β-, γ-tocopherols, as well hydrophilic (H-AOX) lipophilic (L-AOX) activities. ...

objective(s):hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. in the present study, we evaluated the effect of ethanolic extract of ensete superbum seeds (esse) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. materials and methods:glucose, hba1c, total protein, albumin, renal function mark...

The goal of this study was to determine to what extent aging affects the antioxidant defense system of the rat adrenal and to evaluate the impact of any change in this system on the recognized age-related decline in steroidogenic capacity of adrenocortical cells. The studies were conducted on young (2-5 mo) and aging (12-27 mo) Sprague-Dawley rats and involved procedures measuring steroidogenes...

Free radicals are common outcome of normal aerobic cellular metabolism. In-built antioxidant system of body plays its decisive role in prevention of any loss due to free radicals. However, imbalanced defense mechanism of antioxidants and overproduction or incorporation of free radicals from environment to living systems leads to serious damage. It also attacks nervous system resulting in neural...

Objective(s):Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. Materials and Methods:Glucose, HbA1c, total protein, albumin, renal function mar...