We used a computer-based method to help validate the reference ranges of assays for triiodothyronine (T3) and thyroxin (T4). A retrospective search of a database of laboratory results for the previous six months identified all patients with apparent euthyroid status, as defined by methods independent of the immunoassay under review. A computer-generated reference group (CGR Group) of 2001 recor...

OBJECTIVES To define and discuss reference ranges for commonly determined laboratory parameters in healthy adults from southern Tanzania. METHODS A population-based sample of adult volunteers from Mbeya, Tanzania, who were not HIV positive or showing signs and symptoms of other diseases, participated in this study. We enrolled 145 women and 156 men between 19 and 48 years of age to determine ...

Andersen S, Petersen KM, Brunn NH, Laurberg P (2002). Narrow individual variations in serum T4 and T3 in normal subjects: a clue to the understanding of subclinical thyroid disease. Journal of Clinical Endocrinology and Metabolism. 2002;87:1068– 72. Abstract: High individuality causes laboratory reference ranges to be insensitive to changes in test results that are significant for the individua...

BACKGROUND We introduce a new criterion, the percentile inclusion probability, for comparing methods for calculating reference intervals. The criterion is compared with a previously published measure of reliability suggested by Linnet (Linnet K. Clin Chem 1987;33:381-6), the ratio of the width of the confidence interval for the percentile to that of the reference interval. METHODS Data were s...

OBJECTIVE Anti-streptolysin O (ASO) and anti-DNase B (ADB) titers are used for the diagnosis of poststreptococcal complications. Ranges of normal values of ASO and ADB titers vary, depending on age, population and different time intervals. Although many studies have been performed for determination of the ASO titer in our country, only a few studies have been conducted for specification the upp...

Aim. To provide bone status assessment in infancy using quantitative ultrasound (QUS) applied to second metacarpus. Methods. 103 healthy term infants and 3 patients with rickets, aged ≤ 12 months, underwent metacarpal QUS evaluation using QUS DBM Sonic Aurora IGEA (MO, Italy), which measures speed of sound (mcSOS) and bone transmission time (mcBTT). Results. In the total sample, median (interqu...

BACKGROUND/OBJECTIVES To collect the reference values for facial asymmetry in adults using landmark and surface-based three-dimensional analyses and to compare their diagnostic abilities. MATERIALS AND METHODS Laser scans were taken from 85 British Caucasians, 29 males (23.9±5.7 years, range 19-44) and 56 females (28.1±9.5 years, range 19-54), students and staff of the Cardiff Dental Hospital...

During the MaCWAVE campaign, combined rocket, radiosonde and ground-based measurements have been performed at the Norwegian Andøya Rocket Range (ARR) near Andenes and the Swedish Rocket Range (ESRANGE) near Kiruna in January 2003 to study gravity waves in the vicinity of the Scandinavian mountain ridge. The investigations presented here are mainly based on the evaluation of continuous radar mea...

OBJECTIVE Presepsin (soluble CD14 subtype) has been shown to be beneficial as a sepsis marker in adults. Nevertheless, very few data are available in neonates. The aim of the present study was to determine reference ranges of presepsin in term and preterm neonates. METHODS Healthy term neonates and preterm neonates without clinical signs of infection admitted to the Neonatal Unit were consecu...