chronic granulomatous disease (cgd) is a rare primary immunodeficiency disorder due to a genetic defect in one of the components of nicotinamide adenine dinucleotide phosphate (nadph) oxidase complex. this complex is composed of membrane-bound gp91- phox and p22- phox subunits, and cytosolic subunits consisting of p47- phox , p67- phox , and p40- phox . a mutation in cybb gene encoding gp91- ph...

objective this is the first report of cns involvement by the new influenza virus (influenza a [h1n1]) in iran. the patient was a 10-year-old boy with chief complaints of fever, malaise, and cranial nerve involvement, resulting in respiratory muscle paralysis and intubation. this shows that the new influenza virus, as well as the seasonal flu, can cause neurologic complications; however, the sev...

background: the clinical manifestations and outcome of influenza infection differ between various patients in the world. the purpose of this study was to assess the clinical manifestations of patients with confirmed or suspected novel h1n1 flu infection in sari, north of iran. methods: from september 2009 to january 2010, the patients’ data were collected by retrospective chart review of medica...

The present study investigated the prevalence of psychological distress in medical and psychology students (n =293) at a German University. Sampling structure, questionnaire and process of this study were a reproduction of a prior study carried out at the same university in 1994 (n =346) which allowed for assessing changes over time. Results show that 12% of students suffered from clinically re...

This study presents an intuitive explanation, based on insights of real options theory, for the value size puzzle. Growth firms are not overvalued, but priced for their upward potential. Small growth firms are especially characterized by an asymmetric risk-return relation. Therefore, the value-size premium comprises two parts: a distress premium and a growth discount. Beta underestimates the ri...

The goal of this paper is to identify the key financial distress performance indicators of local governments by using published financial data. Thus, using proper financial ratios the financial performance of municipalities is assessed through a multicriteria methodology that combines simulation analysis approach (stochastic multicriteria acceptability analysis) with a disaggregation technique....

Healthcare workers are reporting instances of psychological stress induced by healthcare information technology. IS researchers have established a valuable research program on which to study psychological technostress in healthcare workers. This research stream considers technostress a "dark side" of technology associated with negative perceptions and harmful effects. However, extant literature...

1 Among older people (65 years of age and older), many worry about their health, family, financial situation and mortality. These worries are even more likely to arise when they feel that their physical and mental capacities are diminishing and that they are loosing their autonomy. This is considered as normal anxiety. However, sometimes anxiety is so intense that it causes significant impairme...