Glutaminolysis plays a critical role in nutrient sufficiency and cell signaling activation in mammalian cells. Unexpectedly, our recent investigations revealed that the unbalanced activation of glutaminolysis during nutritional restriction causes a particular form of apoptotic cell death, that we termed "glutamoptosis." We found that the inhibition of autophagy is a key step to allow glutamopto...

Pediatric malnutrition is defined by the Academy of Nutrition and Dietetics and the American Society for Parenteral and Enteral Nutrition as “an imbalance between nutrient requirements and intake that results in cumulative deficits of energy, protein or micronutrients that may negatively affect growth, development and other relevant outcomes” [1]. It represents a serious public health issue lin...

A remarkable amount of data has been compiled that indicates many of the diseases that this middleaged population begins experiencing, (including depression, chronic fatigue syndrome, and heart disease) are directly related to hormone imbalances that are correctable with currently available drug and nutrient therapies. To the patients’ detriment, conventional doctors are increasingly prescribin...

trient concentration in the leaves (Beaufils, 1973). Those dual ratios represent the minimum expression for nutriIn this study, we evaluated the potential of reflectance and fluoresent interactions. Parent and Dafir (1992) developed a cence for the detection of the Compositional Nutrient Diagnosis (CND) N index (IN). The CND reflects nutrient deficiencies as well new indicator of plant nutritio...

The availability of nutrients and the quantity and quality of food at the base of food webs have largely been ignored in discussions of the Phanerozoic record of biodiversity. We examine the role of nutrient availability and phytoplankton stoichiometry (the relative proportions of inorganic nutrients to carbon) in the diversification of the marine biosphere. Nutrient availability and phytoplank...

The intestine is the shared site of nutrient digestion, microbiota colonization and immune cell location and this geographic proximity contributes to a large extent to their interaction. The onset and development of a great many diseases, such as inflammatory bowel disease and metabolic syndrome, will be caused due to the imbalance of body immune. As competent assistants, the intestinal bacteri...

Lack of a uniform definition is responsible for underrecognition of the prevalence of malnutrition and its impact on outcomes in children. A pediatric malnutrition definitions workgroup reviewed existing pediatric age group English-language literature from 1955 to 2011, for relevant references related to 5 domains of the definition of malnutrition that were a priori identified: anthropometric p...