We read with great interest the article by González-Juanatey et al. on the cost-effectiveness of the new oral anticoagulant dabigatran compared with conventional oral anticoagulant therapy (OAT) in patients with nonvalvular atrial fibrillation. This study consisted of a simulation using modern computer models applied to the Spanish setting. It concluded that dabigatran would be an effective str...

Phytochrome A is a member of a plant regulatory photoreceptor family (1). The down-regulation by phytochrome of the transcription of its own PHYA3 gene, is one of the most rapid light-mediated effects on transcription reported to date in plants (2). Two positive elements designated PE1 (-367 bp to -346 bp) and PE3 (-111 bp to -81 bp) necessary for high level expression of the oat PHYA3 gene, we...

We read with great interest the article by González-Juanatey et al. on the cost-effectiveness of the new oral anticoagulant dabigatran compared with conventional oral anticoagulant therapy (OAT) in patients with nonvalvular atrial fibrillation. This study consisted of a simulation using modern computer models applied to the Spanish setting. It concluded that dabigatran would be an effective str...

Background Deficiency of available forms of phosphorus is common in most soils and causes reduction of crop plants growth and yield. Recently, model plants responses to phosphate (Pi) deficiency have been intensively studied. However, acclimation mechanisms of cereals like oat (Avena sativa L.), to low Pi stress remains not fully understood. Oat plants have been usually cultured on poor soils, ...

Ornithine aminotransferase (L-ornithine: 2-oxoacid aminotransferase, OAT, EC 2.6.1.13) plays crucial physiological roles in amino acid metabolism because this enzyme is at the crossroad of several pathways including those of L-arginine, L-ornithine, L-glutamate, Lglutamine, and L-proline. Specifically, OAT catalyzes the transamination of L-ornithine in the presence of α-ketoglutarate to produce...

Background and Objective: Minor dental surgery is invasive and hemorrhagic. Thus, in patients treated with anticoagulants, the bleeding risk related to these invasive procedures is concerning. The aim of this meta-analysis is to evaluate this risk by comparing the post-operative bleeding rates of oral anticoagulation treatment (OAT) patients (without interrupted or altered anticoagulant intake)...

BACKGROUND The relationship between substance use disorders and psychiatric pathology is still an open question. The main aim of the present study was to verify whether the five psychopathological dimensions identified through the SCL-90 tool in a previous study carried out on patients with heroin addiction entering an outpatient opioid agonist treatment (OAT) were also observable in those ente...

OBJECTIVE To use drug-induced sedation endoscopy (DISE) to identify locations and patterns of residual collapse in patients with obstructive sleep apnea (OSA) with incomplete response to oral appliance therapy (OAT). STUDY DESIGN Case series with chart review. SETTING Academic multidisciplinary sleep practice. SUBJECTS AND METHODS Thirty-five consecutively screened adult patients with OSA...

BACKGROUND Soluble fibers lower serum lipids, but are difficult to incorporate into products acceptable to consumers. We investigated the physiological effects of a concentrated oat beta-glucan on cardiovascular disease (CVD) endpoints in human subjects. We also compared the fermentability of concentrated oat beta-glucan with inulin and guar gum in a model intestinal fermentation system. METH...

OBJECTIVES The Joint Commission revised its National Patient Safety Goals (NPSGs) to include oral anticoagulation therapy (OAT) in 2008. We sought to examine the effect of including OAT in The Joint Commission's NPSGs on historically low rates of OAT initiation for individuals with incident atrial fibrillation (AF). SETTING Southeastern state in the USA. PARTICIPANTS North Carolina State He...