aim of present research was to review the probability changes in ghrelin and obestatin hormones following eight weeks aerobic training with moderate intensity in sprague–dawley male rats. for this purpose randomly selected 47 two month age rats from animal lab. all rats made fat by stimulate the appetite with lettuce and vegetables and reached from mean weight 240±15 to 320±20 kg and after that...

UNLABELLED BACKGROUND The present study investigated plasma levels of gut-brain axis peptides ghrelin, obestatin, NPY and PYY after consumption of a high-carbohydrate (HC) and high-protein (HP) breakfast in patients with anorexia nervosa, bulimia nervosa and in healthy controls. These peptides play an important role in regulation of energy homeostasis and their secretion is disturbed under c...

Different iodinated mouse obestatin peptides have been characterized toward their in vitro stability in the main metabolic compartments plasma, liver and kidney. Using HPLC-UV for quantification, significant differences in the degradation kinetics of the iodinated peptides, arising from both enzymatic proteolysis and dehalogenation, were found when compared to the native, unmodified peptide. HP...

Ghrelin and obestatin are gastrointestinal peptides, encoded by the same preproghrelin gene. Both are expressed in breast cancer tissue and ghrelin has been implicated in breast cancer tumorigenesis. Despite recent advances in breast cancer management the need for new prognostic markers and potential therapeutic targets in breast cancer remains high. We studied the prognostic impact of ghrelin ...

Anorexia nervosa (AN) is an eating disorder characterized by restrictive and significant weight loss. In the course of AN, changes are observed in appetite regulation, including orexigenic ghrelin potentially anorexigenic obestatin. The study aimed to determine if any serum obestatin levels during treatment AN observed, while investigating correlations between these peptides severity disturbed ...

Obesity is an escalating health problem in developing countries. One to ten children worldwide are overweight a report showed by the International Task Force. Ghrelin, orexigenic peptide, has 28 amino acids, it considered greatest remarkable promotion last two decades for understanding physiological changes of action regu­lating food intake and hunger. Obestatin 23-amino acid peptide nearly con...