AIM To investigate the prevalence and virological characteristics of occult hepatitis B virus (HBV) infections in patients with hematological malignancies in South Egypt. METHODS Serum samples were collected from 165 patients with hematological malignancies to monitor titers of HBV DNA, hepatitis B surface antigen (HBsAg), and antibodies to HBV core (anti-HBc) and surface antigens. Serum samp...

Submit Manuscript | http://medcraveonline.com Abbreviations: 95%CI: 95% Confidence Interval; ANC: Antenatal Care Attendee; aOR: Adjusted Odds; Ratio; cOR: Crude Odds Ratio; HBV: Hepatitis B Virus; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B Surface Antigen; Anti-HBc: Hepatitis B Core Antibody; Anti-HBe: Hepatitis Be Antibody; Anti-HB: Hepatitis B Surface Antibody; HIV: Human Immunodeficien...

Submit Manuscript | http://medcraveonline.com Abbreviations: 95%CI: 95% Confidence Interval; ANC: Antenatal Care Attendee; aOR: Adjusted Odds; Ratio; cOR: Crude Odds Ratio; HBV: Hepatitis B Virus; HBeAg: Hepatitis B e antigen; HBsAg: Hepatitis B Surface Antigen; Anti-HBc: Hepatitis B Core Antibody; Anti-HBe: Hepatitis Be Antibody; Anti-HB: Hepatitis B Surface Antibody; HIV: Human Immunodeficien...

OBJECTIVES To examine the efficacy of current hepatitis B immuno-prophylaxis and estimate the prevalence of S-mutant infections among local newborn babies. DESIGN Prospective study. SETTING Regional hospital, Hong Kong. PATIENTS A total of 137 newborn babies delivered between the period of November 2000 and 30 June 2001 inclusive, whose mothers were chronic hepatitis B surface antigen car...

Pregenomic RNA (pgRNA) is generated from covalently closed circular DNA (cccDNA) and plays important roles in viral genome amplification and replication. Hepatic pgRNA and cccDNA expression levels indicate viral persistence and replication activity. This study was aimed to measure hepatic pgRNA and cccDNA expression levels in various states of hepatitis B virus (HBV) infection. Thirty-eight hep...

BACKGROUND Hepatitis B virus infection is a very common cause of chronic liver disease worldwide. It is estimated that 3% of Iranians are chronically infected with hepatitis B virus. Current population-based studies on both rural and urban prevalence of hepatitis B virus infection in Iran are sparse with results that do not always agree. We performed this study to find the prevalence of hepatit...

Occult hepatitis B infection (OBI) is still a topic of debate worldwide. It defined as the presence virus (HBV) DNA in serum and/or liver from HBsAg-negative subjects. OBI may lead to development cirrhosis and hepatocellular carcinoma. continues present several unique challenges organ transplantation despite availability an effective vaccine prevent HBV introduction oral therapy treat infection...

Manufacturing new Hepatitis B virus vaccines, specifically by the use of nanoparticles, is of high global interest. In this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis B virus’ surface antigen (HBsAg) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. The physicochemical properties of the conjugate were characteri...