Quantitative validation of gene regulatory networks (GRNs) inferred from observational expression data is a difficult task usually involving time intensive and costly laboratory experiments. We were able to show that gene knock-down experiments can be used to quantitatively assess the quality of large-scale GRNs via a purely data-driven approach (Olsen et al. 2014). Our new validation framework...

We propose a collapse prediction model described in peak ground velocity (PGV) and peak ground displacement (PGD) for steel and reinforced concrete moment-resisting frame buildings. Olsen (2008) simulated the seismic response of eight steel frame buildings to over 60,000 simulated seismic motions; the simulations showed that collapse can be predicted from PGV and PGD. Song and Heaton (2012, als...

Processes at the Mineral}Water and Particle}Water Interface in Natural Systems. New York: John Wiley & Sons. Summers RM (1989) Point and Non-point Source Nitrogen and Phosphorus Loading to the Northern Chesapeake Bay. Maryland Department of the Environment, Water Management Administration, Chesapeake Bay Special Projects Program, Baltimore, MD. Wiltshire KH (1992) The inSuence of microphytobent...

Phosphorus (P) in irrigation runoff may enrich offsite water bodies and streams and be influenced by irrigation water quality and antecedent soil surface conditions. Runoff, soil loss, and P fractions in runoff using reverse osmosis (RO) water or mixed RO and well water (RO/ Tap) were studied in a laboratory sprinkler study to evaluate water source effects on P transport. A top- or subsoil Port...

The tributaries of Lake Whatcom, Austin/Beaver, Anderson, Olsen, and Smith Creeks, provide essential habitat for many fish species native to the Pacific Northwest. However, development in the watershed has contributed to habitat alterations and even degradation of habitat quality. In this report, fish abundance and diversity, and habitat quality is compared both temporally, and among different ...

The lag model proposed by Olsen and Coakley is applied in combination with the baseline k–! two-equation turbulence model to simulate the steady and unsteady transonic  ows in a diffuser. A fully implicit time-accurate multigrid algorithm is used to solve the unsteady Navier–Stokes equations and the coupled k–! turbulence model equations. Two test cases are investigated, one with a weak shock ...

The lag model proposed by Olsen and Coakley (2001) is applied to simulate the steady and unsteady transonic flows in a diffuser. The unsteady flows are induced by imposing fluctuating back-pressures. A fully implicit time–accurate multigrid algorithm is used for solving the Navier-Stokes equations and the coupled k-ω turbulence model equations. Two test cases are investigated, one with a weak s...