introduction: cyclophosphamide (cp) is used for the treatment of various cancers. in spite of its therapeutic importance, a wide range of adverse effects such as reproductive toxicity has been observed following the administration of this drug in human and experimental animals. in the current study, we have investigated the adverse effects of cp on morphology and histology of testis rats. metho...

introduction: toxic effects of pesticides are commonly associated with reactive oxygen species damage and pentoxifylline a phosphodiesterase inhibitor is a drug well known for antioxidant properties. the purpose of this study was to evaluate the oxidative damages following a subacute exposure to malathion, an organophosphorus insecticide and pentoxifylline's ability to counteract these eff...

background: ritalin (methylphenidate methylphenidate) is an amphetamine used to treat adhd, symptoms of narcolepsy, and some people with depression. this study was to investigate the effect of ritalin food on blood albumin and some liver enzymes. materials and methods: in this study, 40 male wistar rats were randomized into 4 groups (1 control group, and three experimental groups). in the contr...

purpose previous studies have shown that physical activity improves learning and memory. present study was performed to determine the effects of short term and long term treadmill exercise on learning, memory consolidation and retrieval of passive avoidance learning in an animal model. methods in this study fifty male wistar rats with 3-4 months of age were randomly divided into five groups (n=...

conclusions: saffron, as an antioxidant, is positively effective on sperm parameters in rats exposed with cadmium. objectives: the aim of this study was to determine the effects of saffron on the results of semen parameters (sperm concentration, motility and viability in cauda of epididymis) in rats exposed to cadmium. materials and methods: thirty wistar male rats were divided into four groups...

objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (otm) in rats. materials and methods: forty male 250-300 g sprague-dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. orthodontic appliances were ligated between the maxillary first molars and in...

background: acute blood purification (abp) therapy is used regularly in the clinical setting and reportedly alleviates organ failure associated with severe systemic inflammatory responses, leading to reduced mortality. the present study aimed to determine whether there is a difference in efficacy between polysulfone (ps) membranes, which are currently used regularly in the clinical setting, and...

background: fatigue is a common side effect in cancer patients undergoing radiation therapy (rt). radiation-induced fatigue affects the quality of life, but there is no definitive treatment option. in this study, the weight-loaded forced swim test was performed to assess the effect of coenzyme q10 (coq10) on radiation-induced fatigue. materials and methods: a total of 60 rats were divided rando...

introduction: nymphea lotus linn (n. lotus) flowers are used empirically for the treatment of male sexual disorders in cameroon west region. this study was aimed to evaluate the effects of the n. lotus on some parameters of male fertility in adult albino male rats. methods: twenty four male rats were divided in 4 groups (n=6 each) and subjected to the following treatment: distilled water as veh...

background : electromagnetic fields are associated with production, transmission and use of electricity. in this  tudy we have investigated the effects of short and long time alternative magnetic fields' (amf, 50 hz) exposure on the secretion of hypothalamic-pituitary-gonadal axis in the male rats. methods : forty eight wistar male rats, same range of age and weight were divided into four group...