Received March 5, 2003 Abstract Immunisation provides protection from infective diseases that have previously caused major mortality and morbidity worldwide. Protection from vaccine preventable diseases should be available to all children globally. During the last two decades, global initiatives have led to significant improvement in vaccine availability for all children, but there is still muc...

The outcome of drug therapy is often unpredictable, ranging from beneficial effects to lack of efficacy to serious adverse effects. Variations in single genes are 1 well-recognized cause of such unpredictability, defining the field of pharmacogenetics (see Glossary). Such variations may involve genes controlling drug metabolism, drug transport, disease susceptibility, or drug targets. The seque...

First, we have to consider who filled out the survey. The response rate was less than 20%, meaning that 4 out of 5 MLA members did not respond. Who are these nonresponders? We can only speculate. My guess is they compose 2 groups: some too busy to take the relatively short survey (34 questions) and the rest just not interested in surveys about research. My estimate is the second was the larger ...

Diffractive optical elements are components relying on the physical phenomena of diffraction and interference to control the propagation of light. Such elements are usually macroscopically planar microstructures, consisting of features with dimensions from a couple of wavelengths to a few tens of microns and being designed by advanced numerical algorithms based on rigorous diffraction theory. T...

This paper discusses the need to recognize and take advantage of arising opportunities when an agent is autonomously interacting with an environment. We discuss the tasks, methods, model framework, and use it to analyze opportunities across several dimensions: when changing the tasks versus changing the methods, when having a complete knowledge about the methods in the domain versus having part...

We propose the Hyper-Kamiokande (Hyper-K) detector as a next generation underground water Cherenkov detector [1]. It will serve as a far detector of a long baseline neutrino oscillation experiment envisioned for the upgraded J-PARC beam, and as a detector capable of observing, far beyond the sensitivity of the Super-Kamiokande (Super-K) detector, proton decays, atmospheric neutrinos, and neutri...

Package ”Automatica” is intended for analysis and development of control algorithms for plants, considering parametric and structural uncertainty and influence of unknown-butbounded disturbance. The package is intended for scientists and developers of real-world control systems. The goal of an engineer is to guarantee given steady-state error tolerance for each of the controlled variables while...