نتایج جستجو برای: orally disintegrating tablets (odt)

تعداد نتایج: 40653  

2007
Jörg Czekalla Thomas Wagner Alexander Schacht Michael Kluge Bruce Kinon

BACKGROUND This study compared effectiveness and acceptance of orally disintegrating olanzapine tablets (ODT) with standard-coated tablets (SOT) in acutely ill psychiatric patients admitted to psychiatric hospitals for emergency treatment. METHODS Large, prospective, observational study at hospital emergency units across Germany in patients with a diagnosis or tentative diagnosis of acute sch...

Journal: :the iranian journal of pharmaceutical research 0
zahra hesari dept. of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran akram shafiee dept. of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran 1417614411, iran shirin hooshfar school of pharmacy, shaheedbeheshti university of medical sciences, tehran, iran. naser mobarra stem cell research center, department of biochemistry, school of medicine, golestan university of medical sciences, gorgan, iran seyedalireza mortazavi school of pharmacy, shaheedbeheshti university of medical sciences, tehran, iran.

orally disintegrating tablets (odt) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. we focused on taste masking and formulation of ranitidine odt which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Journal: :Chemical & pharmaceutical bulletin 2012
Keita Kondo Toshiyuki Niwa Kazumi Danjo

This report describes a new disintegration tester that can determine not only the disintegration time of orally rapidly disintegrating tablets (ODT), but also the disintegration behavior and mechanism. Using the tester, the disintegration properties of the tablets prepared in a previous study were examined. The purpose of this study is to confirm the utility of the tester as an instrument for e...

2012

----------------------------RECENT MAJOR CHANGES--------------------­ Addition of new dosage strength: ARICEPT 23 mg ----------------------------INDICATIONS AND USAGE---------------------­ ARICEPT is an acetylcholinesterase inhibitor indicated for the treatment of dementia of the Alzheimer’s type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer’s Disease (1.0).

2014
Sharda kumari P. K Sharma

Drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and biochemical parameters pertinent to their performance. Over the three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance....

Journal: :Psychiatria Danubina 2009
Oliver Kozumplik Suzana Uzun Miro Jakovljević

The aim of this article is to report weight loss in patients with schizophrenia after switching from olanzapine standard oral tablet (SOT) to olanzapine orally disintegrating tablets (ODT). In the first case report, the patient was switched to olanzapine ODT in daily dosage of 20 mg, while in the second case report, the patient was switched to olanzapine ODT in daily dosage of 15 mg, and weight...

2011
Rhys J. Jones Ali Rajabi-Siahboomi Marina Levina Yvonne Perrie Afzal R. Mohammed

Gelatin is a principal excipient used as a binder in the formulation of lyophilized orally disintegrating tablets. The current study focuses on exploiting the physicochemical properties of gelatin by varying formulation parameters to determine their influence on orally disintegrating tablet (ODT) characteristics. Process parameters, namely pH and ionic strength of the formulations, and ball mil...

2010
Farhan AlHusban Amr M. ElShaer Jiteen H. Kansara Alan M. Smith Liam M. Grover Yvonne Perrie Afzal R. Mohammed

Lyophilised orally disintegrating tablets (ODTs) have achieved a great success in overcoming dysphagia associated with conventional solid dosage forms. However, the extensive use of saccharides within the formulation limits their use in treatment of chronic illnesses. The current study demonstrates the feasibility of using combination of proline and serine to formulate zero sacharide ODTs and i...

Journal: :journal of reports in pharmaceutical sciences 0
mohammad ali shahtalebi faculty of pharmacy and pharmaceutical sciences.isfahan university of medical science majid tabbakhian faculty of pharmacy and pharmaceutical sciences.isfahan university of medical science navid sarbolookzadeh harandi faculty of pharmacy and pharmaceutical sciences.isfahan university of medical science

difficulty in swallowing (dysphagia) is common among all age groups, especially in elderly and children. orally disintegrating tablets constitute an innovative dosage form that overcomes the problems of swallowing and provides a quicksetof action. the purpose of this study was to formulate and evaluate an orally disintegrating tablet (odt) containing captopril while using croscarmellose sodium,...

2010
Bin Du Xiaotian Li Qiuying Yu Youmei A Chengqun Chen

The goal of this study was to compare the pharmacokinetics of nicardipine hydrochloride orally disintegrating tablets and β-cyclodextrin inclusion complex with its conventional tablets. Forty-five rats were divided into three groups evaluating the effect of dosage forms on the pharmacokinetics of nicardipine hydrochloride. Blood samples were taken at predefined sampling points 0–24h after medic...

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