The effects of acute and subacute toxicity of 1,8-cineole in Kunming mice were studied. After acute oral administration, the LD50 value (95% CL) was 3849 mg/kg (3488.8~4247.1 mg/kg). In the subacute toxicity study, there were no significant differences in body weight and relative organ weight between the control group and 1,8-cineole treatment groups. The histopathological examinations showed t...

BACKGROUND Methamphetamine is one of the most toxic of the drugs of abuse, which may reflect its distribution and accumulation in the body. However no studies have measured methamphetamine's organ distribution in the human body. METHODS Positron Emission Tomography (PET) was used in conjunction with [(11)C]d-methamphetamine to measure its whole-body distribution and bioavailability as assesse...

The aim of the present study was to investigate the testosterone-like effect of Kaempferia parviflora (KP). Castrated immature rats were randomized and divided into two groups (control and KP-treatment groups). The rats (n=7-8) were treated daily for 5 days by oral route with water in the control group and 1,000 mg/kg of KP in the treatment group. All rats were decapitated 24 h after their last...

Rat pups were artificially reared (AR) from post-natal day 5 by intermittent gastric infusion. Mother-reared (MR) siblings served as controls. Fourteen measures of body and organ growth were taken at the end of each experiment. In Expt 1, two batches of pups were given rats' milk only, obtained by manual expression from anaesthetized dams. The first batch, reared to 12 d, grew less well than th...

Background: The aim of this study was to clarify the relationship between the sexual reproduction and the resource allocation in a natural Polygonatum humile population grown in a temperate mixed forest gap. For this aim, the plant size, the node which flower was formed, the fruiting rate, and the dry weight of each organ were monitored from June 2014 to August 2015. Results: Firstly, in 3–13-l...

In rats fasted after the removal of about seven-tenths of the liver the remaining fragment undergoes ordinarily a marked simple hypertrophy and attains the weight reached through a process of simple atrophy by the entire liver of fasting controls. Under circumstances of exceptionally severe inanition, the hypertrophy may not occur, the fragment remaining unchanged or even undergoing a slight at...

In-vivo studies were carried out on albino rats fed “Onunu” and “Mgbam”, traditional diets of the Ikwerre people of the Niger Delta, Nigeria. In this study, the test diets (“Onunu” and “Mgbam”) were prepared using the ordinary traditional cooking methods, the reference diet was Nutrend (a commercial infant food) while the basal or protein-free diet was formulated using corn starch, palm oil, vi...

UNLABELLED Limitations of current methods: Normalization of resting energy expenditure (REE) for body composition using the 2-compartment model fat mass (FM), and fat-free mass (FFM) has inherent limitations for the interpretation of REE and may lead to erroneous conclusions when comparing people with a wide range of adiposity as well as before and after substantial weight loss. EXPERIMENTAL ...

conclusions this study shows that an adequate nutritional support, in patients with severe burn injury, can improve sofa score. it is also more cost-effective, resulting in a shorter los in hospital. background severe burned patients developed metabolic imbalances and systemic inflammatory response syndrome (sirs), which can lead to malnutrition, impaired immunologic response, multiple organ fa...