We report the synthesis of extended two-dimensional organic networks on Cu(111), Ag(111), Cu(110), and Ag(110) from thiophene-based molecules. A combination of scanning tunnelling microscopy and X-ray photoemission spectroscopy yields insight into the reaction pathways from single molecules towards the formation of two-dimensional organometallic and polymeric structures via Ullmann reaction deh...

This Thematic Series is dedicated to the memory of Professor Peter Hofmann (Figure 1) whose research work included many seminal contributions to the field of organometallic chemistry [1-3]. Organometallic chemistry has therefore been chosen as the topic of this Thematic Series of the Beilstein Journal of Organic Chemistry. Over a period of many decades, the chemistry of metal–carbon bonds has g...

Recently, solid-phase synthesis has been recognized as an important methodology for combinatorial chemistry or automated synthesis directed at drug discovery. Various synthetic methodologies have been applied to solid-phase synthesis, although it appears that organometallic chemistry in this area is still being explored. In solution-phase chemistry, organometallic reagents have been utilized fo...

Electron beam deposition ~EBD! provides an inexpensive way to fabricate nanostructures of various materials in a scanning electron microscope ~SEM!. However, the purity of metals deposited from an organometallic precursor gas is impaired by simultaneously deposited carbon coming both from the organometallic molecule and the residual contamination gas in the SEM chamber. We discuss carbon-contam...

Esterification of (4-hydroxyphenyl)diphenylphosphine, coordinated to the [Ru(η6-p-cymene)Cl2] fragment, allows a series of bioactive carboxylic acids to be introduced directly into the organometallic molecule. Evaluation of the compounds on human ovarian cancer cells reveals synergistic enhancements in their antiproliferative activity relative to their bioactive organic and organometallic precu...

Introduction Conclusions References

When coenzyme B(12) was identified as organometallic derivative of vitamin B(12), metal-carbon bonds were revealed to be relevant in life processes. Vitamin B(12), the "antipernicious anaemia factor" required for human health, was isolated earlier as a crystallizable cyano-Co(III)-complex. B(12) cofactors and other cobalt corrinoids play important roles not only in humans, but in the metabolism...