We are reporting four cases of acquired double orifice mitral valve (DOMV) of rheumatic etiology (rare) presenting as significant mitral stenosis (MS) treated successfully by percutaneous intervention. All four patients are young (3 males, 1 female) who presented with dyspnea of Newyork heart association (NYHA) class II with mean duration of 1.3 years. Typical clinical findings of MS were prese...

BACKGROUND Flow-rate dependencies of the Doppler continuity equation are addressed in this study. METHODS AND RESULTS By use of computational fluid dynamic (CFD) software with turbulence modeling, three-dimensional axisymmetric models of round stenotic orifices were created. Flow simulations were run for various orifice area sizes (0.785, 1.13, 1.76, and 3.14 cm2) and flow rates (0.37 to 25.0...

Background—The edge-to-edge technique is an accepted method for the surgical repair of a regurgitant mitral valve. This study reports the initial use of an endovascular technology that enables a double-orifice edge-to-edge mitral valve repair without cardiopulmonary bypass in an animal model. Methods and Results—Adult pigs (n 14) were anesthetized, and left thoracotomy was performed for epicard...

Regurgitant flow was analysed in 40 cases of mitral regurgitation, using combined ultrasonic pulsed Doppler technique and two dimensional echocardiography. Abnormal Doppler signals indicative of mitral regurgitant flow were detected in reference to the two dimensional image of the long axis view of the heart and the short axis view at the level of the mitral orifice. The overall direction of re...

OBJECTIVES To carefully collect samples from the external urethral orifice, navicular fossa, and penile urethra and perform a semiquantitative evaluation and identification of gram-positive and gram-negative bacteria present in the normal male urethra. METHODS Thirty uncircumcised male patients 18 to 40 years old without any inflammatory and/or infectious urethral processes were enrolled in t...

Introduction: In human heart, right atrio-ventricular orifice is guarded by tricuspid valve, which lies at the junction of right atrium and right ventricle of the heart controlling and directing unidirectional blood flow during ventricular diastole. Irreparable damage to tricuspid valve calls for its replacement using prosthetic valves. Prosthesis of these synthetic valves need detail knowledge...

Clinical assessment of the severity of mitral stenosis sometimes presents difficulties. The symptoms may be obscured by superadded effort syndrome or by limitation of activity imposed by the patient's doctor. The physical signs may reveal the presence of pulmonary hypertension or heart failure, but in their absence there may be little indication as to the size of the mitral orifice. The intensi...

OBJECTIVES The purpose of this study was to quantify and characterize the regurgitant flow pattern and regurgitant orifice area in patients undergoing therapy for severe heart failure using contemporary echocardiographic techniques. BACKGROUND Mitral regurgitation may be dynamic in patients with heart failure and ultimately correlate with outcome in a group of patients. METHODS Fourteen pat...

To cite: Prakash J, Goel A, Kumar M, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200168 DESCRIPTION A 42-year-old man presented with a 2-day history of severe colicky pain in the left flank with vomiting. X-ray (figure 1A) and ultrasonography showed a 13 mm left vesicoureteric junction calculus (figure 1B) with moderate hydroureteronephrosis and sma...

OBJECTIVE To investigate the impact of transgastric peritoneal access on plasma biomarkers of acute inflammatory response in comparison to laparoscopy. METHODS This was a prospective and comparative study in a porcine model. Transgastric peritoneal access performed by natural orifice transluminal endoscopic surgery was compared with laparoscopy. Laparotomy and sham groups were used as positiv...