Background and Objective: Dyskinesia is a debilitating complication of Parkinsonchr('39')s disease (PD), which appears due to some known risk factors. The effect of diabetes and high plasma glucose on the manifestation of dyskinesia has been evaluated in just a few previous reports. The current study aimed to assess the mentioned correlation. Materials and Methods: In this case-control study, ...

In developed countries, orofacial pain is one condition in dentistry that has been well defined, explored, and managed. Unfortunately, unlike the grown and developed management of orofacial pain in developed countries, the management of orofacial pain in developing countries is still poorly performed. The current article discusses about the current management of orofacial pain in developing cou...

background: currently, orofacial sequelae are recognized as very influential on the qualityof- life for a victim of orofacial damage. therefore, correct forensic assessment for indenisation purposes is mandatory. however, orofacial damage is frequently reduced to organic components, which results in a forensic assessment process, which are inadequate. this study aims to improve the orofacial da...

L-3,4-dihydroxyphenylalanine (L-DOPA) is the most common treatment for patients with Parkinson's disease (PD). However, long term use of L-DOPA for PD therapy lead to abnormal involuntary movements (AIMs) known as dyskinesia. Fatty acid amide hydrolase (FAAH) is enriched protein in basal ganglia, and inhibition of the protein reduces dyskinetic behavior of mice. Palmitoyl serotonin (PA-5HT) is ...

In an attempt to define clinically relevant models of akinesia and dyskinesia in 6-hydroxydopamine (6-OHDA)-lesioned rats, we have examined the effects of drugs with high (L-DOPA) vs. low (bromocriptine) dyskinesiogenic potential in Parkinson's disease on three types of motor performance, namely: (i) abnormal involuntary movements (AIMs) (ii) rotational behaviour, and (iii) spontaneous forelimb...

Anticonvulsants cause dyskinesias more commonly than has been appreciated. Diphenylhydantoin (DPH), carbamazepine, primidone, and phenobarbitone may cause asterixis. DPH, but not other anticonvulsants, may cause orofacial dyskinesias, limb chorea, and dystonia in intoxicated patients. These dyskinesias are similar to those caused by neuroleptic drugs and may be related to dopamine antagonistic ...

As shown for many years and studied again by Chambi-Rocha et al. in this issue of the Journal, chronic mouth breathing during active craniofacial development of a child may result in anatomical changes that directly affect the airway. These changes may result in greater airway instability and collapsibility that potentially lead to other problems later in life, such as sleep-disordered breathin...