BACKGROUND Matrix Gla protein (MGP) is an extrahepatic protein that is dependent on glutamate carboxylation, a vitamin K-dependent process. Its dysfunctional form, desphospho-uncarboxylated-MGP, has been associated with increased arterial calcification and stiffness. The aim of this study was to measure the degree of postoperative carboxylation of MGP and two other Gla proteins in patients sche...

Manual therapists question integrating manual lymphatic drainage techniques (MLDTs) into conventional treatments for athletic injuries due to the scarcity of literature concerning musculoskeletal applications and established orthopaedic clinical practice guidelines. The purpose of this systematic review is to provide manual therapy clinicians with pertinent information regarding progression of ...

PURPOSE The purposes of this study were to identify the pathologic findings of sinus tarsi syndrome (STS) by subtalar arthroscopy and to evaluate the results of arthroscopic treatments in 33 consecutive cases. METHODS A retrospective review was performed in 31 consecutive patients (33 cases) who underwent subtalar arthroscopic treatment for STS. The mean follow-up duration was 24 months (rang...

Staphylococcus comprises up to two-thirds of all pathogens in orthopaedic implant infections with two species respectively Staphylococcus aureus and Staphylococcus epidermidis, being the predominate etiological agents isolated. Further, with the emergence of methicillin-resistant S. aureus (MRSA), treatment of S. aureus implant infections has become more difficult, thus representing a devastati...

The development of a computer based orthopaedic surgical system, with a clear surgical application and a commercial objective, requires the identification of the orthopaedic surgical principle it aims to solve. Other requirements of such a system include: its perceived advantages, its surgically acceptable format and the issues that will be encountered during its development. This paper identif...

SIMULATION INTO THE VIRTUAL ORTHOPAEDIC UNIVERSITY S. GRANGE, G.B WILLS, N. HUMPHREY, J. BURRILL, T. BUNKER, D. DEROURE Department of Education, Royal College of Surgeons of England, United Kingdom IAM Group, Electronics & Computer Science, University of Southampton, United Kingdom Salisbury District Hospital, Salisbury, United Kingdom Princess Elizabeth Orthopaedic Centre, Exeter, United Kingd...

Extremity injuries make up 54% of combat wounds sustained in Operation Iraqi Freedom and Operation Enduring Freedom. In a cohort of war-wounded service members, we identified the conditions secondary to battle injury that result in disqualification from continued service. The Army Physical Evaluation Board records of 464 wounded service members who were injured between October 2001 and January ...

The loss of bone integrity can significantly compromise the aesthetics and mobility of patients and can be treated using orthopaedic implants. Over the past decades; various orthopaedic implants; such as allografts; xenografts and synthetic materials; have been developed and widely used in clinical practice. However; most of these materials lack intrinsic osteoinductivity and thus cannot induce...

During my early orthopaedic training, between 1936 and 1939, I failed to appreciate the full horror ofbone and joint tuberculosis, with its protracted treatment and crippling results; I encountered several cases during the war, but it was not until I became superintendent of the Derby County Tuberculosis and Orthopaedic Service in 1947 that this was borne in on me. The Orthopaedic Hospital at B...