The hip replacement is a surgical procedure to replace the femoral head and acetabulum with prosthetic implants to improve function, increase mobility, and relieve pain caused by damage from disorders such as osteoarthritis and fractures. In recent years, we have seen several recalls of poorly functioning implant systems, most recently, the Johnson and Johnson (J&J) Articular Surface Replacemen...

In order to impede infection and achieve accelerated wound healing in the postorthopaedic surgery patients, a simple and benign procedure for creating nanotubular or nanofibrillar structure of photoactive TiO(2) on the surface of Ti plates and wires is described. The nanoscale TiO(2) films on titanium were grown by hydrothermal processing in one case and by anodization in the presence of dilute...

Probably for as long as surgeons have implanted artificial hips and knees, manufacturers enjoyed the enviable position of being able to set prices. Unable to fall back to the relative safety net of group purchasing contracts and finding themselves compelled to cede to surgeons’ demands for their implant product and supplier of choice, hospitals had little alternative but to pay for the implant,...

No one could believe I’d had two knees replaced”, says 61-year-old Jacquelyn Winn. In 2010, Winn traveled more than 2,800 miles across Japan to fulfill her dream of seeing Mt. Fuji. “I kept up with the activities and didn’t need any extra breaks. We walked an average of 10 miles a day.” The decision to undergo joint replacement surgery is difficult and worrisome for patients like Winn. She suff...

Ubiquicidin (UBI) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. We aimed to assess diagnostic value of 99mTc-UBI [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. Nine patients suspected for orthopedic implant infection, all ...

Ubiquicidin (UBI) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. We aimed to assess diagnostic value of 99mTc-UBI [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. Nine patients suspected for orthopedic implant infection, all ...

BACKGROUND Polyether-ether-ketone (PEEK), cobalt-chromium-molybdenum (CoCrMo), and highly cross-linked polyethylene (HXLPE) are biomaterials used in orthopedic implants; their wear particles are considered to induce peri-implant osteolysis. We examined whether different particle types induce the same degree of peri-implant osteolysis. METHODS Forty female rabbits were randomly divided into fo...