In traditional medicine, Jasonia glutinosa (L.) DC or rock tea (RT) has been mainly used to treat digestive and respiratory pathologies but also as an antimicrobial antidepressant herbal remedy. An ethanolic extract of RT demonstrated have antioxidant anti-inflammatory effects, which may be explained by its phytochemical profile, rich in polyphenols pigments. The aim this study is investigate t...

Food and other environmental factors affect gene expression and behaviour of animals. Differences in bacterial food affect the behaviour and longevity of Caenorhabditis elegans. However, no research has been carried out to investigate whether bacteria could utilize endogenous RNAs to affect C. elegans physiology. Here we show that two Escherichia coli endogenous noncoding RNAs, OxyS and DsrA, i...

Caffeine is a widely used psychoactive substance. Studies have shown that caffeine may play a protective role in aging-associated disorders. However, the mechanisms by which caffeine modulates aging are not yet clear. In this study, we have shown that caffeine increases Caenorhabditis elegans lifespan, delays its larval development, reduces reproduction and body length. These phenotypes were pa...

Scientific research experiences are beneficial to students allowing them gain laboratory and problem-solving skills, as well foundational skills in a team-based setting. We designed module provide guided experience stimulate curiosity, introduce experimental techniques, with needed for higher levels of inquiry. In this module, learn about RNA interference (RNAi) codon optimization using the org...

BACKGROUND: Cocoa, a significant contributor of polyphenols to the western diet has been shown be effective against Aβ induced toxicity in vitro. However, effects long-term cocoa supplementation on behavioural deficits, particularly short-term memory loss observed human AD are not well defined. OBJECTIVE: This study characterized phenotype pan-neuronal expressing C. elegans strain and investiga...