To explore the role of mPer2 in the circadian oscillation in the mammalian cellular clock, we established fibroblast cell lines in which expression of mPer2 is controlled through a tetracycline-regulatable promoter. We revealed that constitutive expression and overexpression of mPer2 mRNA severely impair serum shock-induced cyclic circadian clock gene expression. Moreover, under conditions of l...

This paper demonstrates a thermally actuated tapping mode atomic force microscopy (AFM) with a polymer cantilever. The cantilever (350x250x3 microm(3)) is made from polyimide and includes an embedded resistive heater for thermal actuation. The oscillation of the cantilever is due to the stress gradient caused by alternating heating and cooling from the periodic ac excitation of the heater. The ...

Resonance driving terms can be derived from the frequency analysis of turn-by-turn betatron oscillation data. This paper demonstrates that the same information can also be drawn from the spectral analysis of a driven oscillation adiabatically excited by an rf dipole. The advantage of this method is that a large betatron oscillation amplitude can be sustained without loosing the coherence signal...

The molecular players of circadian clock oscillation have been identified and extensively characterized. The epigenetic mechanisms behind the circadian gene expression control has also been recently studied, although there are still details to be illucidated. In this review, we briefly summarize the current understanding of the mammalian clock. We also provide evidence for the lack of circadian...

Parametric enhancement of the appearance probability of the neutrino oscillation under the inhomogeneous matter is studied. Fourier expansion of the matter density profile leads to a simple resonance condition and manifests that each Fourier mode modifies the energy spectrum of oscillation probability at around the corresponding energy; below the MSW resonance energy, a large-scale variation mo...

In this note we investigate the impact of new physics in the form of general four-fermion interactions on neutrino oscillation signals. We develop a field theoretic description of the overall oscillation process which includes the non-standard interactions during the neutrino production, propagation and detection stages. Insights gained during the development of this formalism regarding the pos...