results out of 140 samples of oca, 70 (50%) samples were malignant cancer and 70 (50%) were benign cancer as the control group. out of 70 malignant samples 25 (36.0%) were hpv-16 positive. 2.8% of the tissue samples of the control group were positive for hpv-16. conclusions these results show a feasible role of hpv-16 in the carcinogenesis of oca. according to these results, infection with hpv ...

background and objective: it is well known that menstrual period and ovarian function are affected by chemotherapy. although breast cancer is the most common cause of chemotherapy in women and ovarian hormones have very important direct and indirect effects on overall survival, disease-free survival, and life quality of patients, but few studies have addressed the frequency and related factors ...

background: although several studies have investigated the association between ovarian cancer risk and nonisoflavone flavonoids intake, these findings are inconsistent. this systematic review of published epidemiological studies was conducted to summarize and clarify the evidence on the association between ovarian cancer incidence and nonisoflavone flavonoids intake. materials and methods: pubm...

background : this study evaluated the role of family history of cancer and gynecologic factors in relation to the etiology of ovarian cancer in a low socioeconomic population in iran. methods : from 2007-2009 we conducted a screening program on women with insurance coverage provided by the imam khomeini relief foundation. a total of 26788 women participated in this study of whom 76 cases had ov...

gonadotropin releasing hormone (gnrh) plays a key role in reproduction. this decapeptide is synthesized and released by hypothalamus and induces the pituitary gonadotrop cells to release pituitary gonadotropin hormones. in some extrapituitary compartments gnrh and its receptor act as part of the autocrine regulatory system of cell proliferation. the anticancer activity of gnrh and its analogues...

objective: to report involvement of the central nervous system (cns) following epithelial ovarian cancer is rare. advances in management of ovarian cancer by use of primary surgery including abdominal hysterectomy, bilateral salpingo'oophorectomy should attain as complete a cytoreduction as possible and effective platinum-based chemotherapy have prolonged survival. case report: we present a cas...

objective: the goal of this study is to evaluate the efficacy of intraperitoneal (jp) cisplatin as consolidation treatment, in epithelial ovarian cancer patients with pathologically negative surgical reassessment, following first-line platinum-based chemotherapy. methods: this study included 22 patients with figo stage (iic- iv) epithelial ovarian cancer (eoc) which had no evidence of disease a...

ovarian cancer is the most lethal gynecological cancer in which cisplatin-based treatment plays fundamental role as the first line chemotherapy option. however, development of platinum-resistance is a critical and poorly understood problem in ovarian cancer treatment. although in vitro generation of platinum-resistant ovarian cancer cell lines is a long established approach to uncover the molec...

primary fallopian tube carcinoma is a rare tumor that histologically and clinically resembles epithelial ovarian cancer. here we introduce a case of tubal carcinoma in a postmenopausal woman. the diagnosis of primary fallopian tube carcinoma is rarely considered preoperatively and is usually first appreciated by the pathologist. because of low frequency of tubal carcinoma, there are few systemi...

background: we examined epidemiological aspects of dynamic changes in incidence of ovarian cancer in women of kazakh and russian nationalities in kazakhstan. methods: the material of investigation was primary data on registered patients with malignant ovarian tumors in the whole country. the study was conducted during the period of 1999-2009. evaluation of changes in ovarian cancer incidence in...