A direct oxidative cross-dehydrogenative coupling (CDC) of N-aryl tetrahydroisoquinolins with 5H-oxazol-4-ones catalyzed by CuBr using air as the only oxidant has been developed, which could also proceed smoothly under a metal-free oxidative system with PhI(OAc)2 as the oxidant. A series of alkylated tetrahydroisoquinolin derivatives were obtained in good yields and excellent diastereoselectivi...

The catalytic water-oxidation activity of Wilkinson's iridium acetate trimer (1) has been characterized electrochemically and by using chemical oxidants. We show that 1 can function as an operationally homogeneous water-oxidation catalyst when driven with sodium periodate as a primary oxidant, but rapidly decomposes using Ce(IV) as a primary oxidant.

The NHPI and palladium cocatalyzed radical oxidative acylation of arenes with aldehydes and alcohols as acyl equivalents via selective C-H functionalization has been described. Molecular oxygen, the most environmentally friendly oxidant, was used as the terminal oxidant in this catalytic cycle.

52 Exogenous oocyte secreted factors such as bone morphogenetic protein 15 (BMP15), together 53 with hormones traditionally used during in vitro oocyte maturation, increase the developmental 54 competence of cumulus oocyte complexes (COCs). Separately, FSH and BMP15 induce 55 different metabolic profiles within COCs, namely FSH increases glycolysis while BMP15 56 stimulates FAD and NAD(P)H auto...

Toxic oxygen species have been implicated as important mediators of injury after reperfusion of an ischemic organ. The aim of this study was to determine if prior metabolic inhibition, such as that which occurs during ischemia, potentiates oxidant injury in vitro. Bovine pulmonary artery endothelial cells were metabolically inhibited for various periods of time with or without the mitochondrial...