Purpose of review The role of antioxidants in the management of hearing loss has generated considerable interest over the past several years. Research efforts in this field have yielded many new insights into the molecular and cellular nature of several types of hearing impairment, including age-related, noiseinduced, and drug-induced hearing loss. The objective of this paper is to highlight so...

The clean and facile electrochemical synthesis of hypervalent iodine reagents is a fast growing field. In the past 5 years, diverse number reaction types have been established, from fluorinations, oxidative cyclizations, C−N C−H couplings oxidations. Electrochemistry beneficial in terms sustainability as requirement for chemical oxidants eliminated. This contributes to cleaner processes with li...

the role of oxygen free radicals in the initiation, promotion and progression of carcinogenesis and the protective role of anti-oxidant defenses has been the subject of much speculation in the recent past with conflicting reports in the literature. in recent years, increasing experimental and clinical data have provided compelling evidence for the involvement of oxidative stress in a large numb...

The present study was aimed to enzymatic antioxidants (superoxide dismutase, catalase, polyphenol oxidase), nonenzymatic (saponin, flavonoids, ascorbic acid and tannin), anti-oxidant ability assays (total anti-oxidant, hydroxyl radical scavenging ability, reducing power activity, inhibition of lipid peroxide formation, DPPH activity metal chelating assay) in I. marginata leaves whole plant. res...

We anticipate high-valent metal–fluoride species will be highly effective hydrogen atom transfer (HAT) oxidants because of the magnitude H−F bond (in product) that drives HAT oxidation. prepared a dimeric FeIII(F)−F−FeIII(F) complex (1) by reacting [FeII(NCCH3)2(TPA)](ClO4)2 (TPA=tris(2-pyridylmethyl)amine) with difluoro(phenyl)-λ3-iodane (difluoroiodobenzene). 1 was sluggish oxidant, however, ...

Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting disruption redox signaling control causing molecular damage. related to a variety diseases, for example, cardiovascular neurodegenerative infections, cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity subtle way through signaling...

The effectiveness of certain non-tocopherol anti-oxidants in preventing or delaying the appearance of signs of vitamin E deficiency in various species has been demonstrated. These deficiency syndromes include exudative diathesis (Dam, Kruse, Prange & Smdergaard, 195 I ) and encephalomalacia (Singsen, Bunnell, Kozeff, Matterson & Jungherr, 1955) in the chick, resorption-gestation in the rat (Dam...