Studies regarding macroalgal responses to ocean acidification (OA) are mostly limited to short-term experiments in controlled conditions, which hamper the possibility to scale up the observations to long-term effects in the natural environment. To gain a broader perspective, we utilized volcanic CO2 vents as a "natural laboratory" to study OA effects on Sargassum vulgare at different time scale...

Objective: The present study was intended to examine whether administration of aqueous extract of the leaves of Ocimum sanctum L. (Tulsi) do possess a protective effect against cadmium-induced oxidative stress in rat heart. Methods: Male albino rats were divided into four groups; control, cadmium treated, aqueous extract protected and only aqueous extract treated (positive control). The rats we...

In nanoimprint lithography, a surface oxidation process is needed to produce an effective poly(dimethylsiloxane) coating that can be used as an anti-adhesive surface of template molds. However, the conventional photooxidation technique or acidic oxidative treatment cannot be easily applied to polymer molds with nanostructures since surface etching by UV radiation or strong acids significantly d...

Introduction Breast cancer is the most common cancer among western women. Except for inherited mutations in the BRCA1, BRCA2, ATM, and p53 genes, little is known about the genetic risk factors for breast cancer. Recently, polymorphisms in genes involved in repair of DNA double-strand breaks were associated with risk of breast cancer (1). It has been proposed that oxidative stress contributes to...

Varicocele-related sperm damages are usually caused by oxidative stresses. Growing evidence indicates that lncRNA growth arrested DNA-damage inducible gene 7 (gadd7) is involved in the regulation of the oxidative stress responses. In this study, we measured the expression level of gadd7 in the sperm and found that the expression of gadd7 was significantly up-regulated in patients with varicocel...

In recent years, the studies on the roles of caffeic acid phenethyl ester (CAPE) in several disease models and cell cultures are tremendously growing. It is such a great molecule that was used by ancient times to ameliorate some diseases and nowadays, it is used by modern medicine to test the effectiveness. In this mini-review article, the protection capability of CAPE, as a liposoluble antioxi...

Oxidative stress is the imbalance between production of reactive oxygen species (ROS) and ability of the biological systems to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of tissues can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell including proteins, lipi...

Glaucoma is the leading cause of irreversible blindness and visual impairment, affecting more than 80 million individuals worldwide. Oxidative stress inflammation-induced neurodegenerative insults to retinal ganglion cells are main pathogenesis glaucoma. Retinal cells, neurons transmitting signals cortex in brain, have very limited regeneration or recovery capacity after damages. Apart from int...