Spray drying is a promising method for the stabilization of vaccines, which are usually formulated as liquids. Usually, vaccine stability is improved by spray drying in the presence of a range of excipients. Unlike freeze drying, there is no freezing step involved, thus the damage related to this step is avoided. The edge of spray drying resides in its ability for particles to be engineered to ...

The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadsheet software. The output of the model was first fitted to the experimental output of a Büchi B-290...

This paper presents a novel interface for 3D modeling in augmented reality, aiming at developing a form gradually in the early phase of a product design process. Previous VR/AR based modeling systems have focused largely on geometrical algorithms and system performance issues. From a designers’ perspective, this study analyzed the conventional form creating processes and developed a more intuit...

objective(s): this study was performed aiming to investigate the effect of particle engineering via spray drying of hydroalcoholic solution on solid states and physico-mechanical properties of acetaminophen.   materials and methods: spray drying of hydroalcoholic solution (25% v/v ethanol/water) of acetaminophen (5% w/v) in the presence of small amounts of polyninylpyrrolidone k30 (pvp) (0, 1.2...

This paper presents the details of a numerical study aimed at investigating fire performance carbon-fiber-reinforced polymer (CFRP)-strengthened short square hollow section (SHS) steel columns with and without an insulation system. Steady- transient-state finite-element (FE) models were developed to simulate behavior CFRP-strengthened exposed uniform elevated temperatures insulated standard con...

Abstract A salt spray test was used to evaluate the corrosion resistance of pickling high-strength steel JSH440W phosphating film on its surface, and scanning electron microscope (SEM) energy dispersive spectrometer (EDS) were analyze micro-morphology element content surface defects area sample after test. The results show that enrichment Si, Mn, O elements badly influences film-forming perform...

The mixture formation prior to the ignition process plays as a key element in the diesel combustion. Parametric studies of mixture formation and ignition process in various injection parameter has received considerable attention in potential for reducing emissions. Purpose of this study is to clarify the effects of injection pressure on mixture formation and ignition especially during ignition ...

This paper presents a novel interactive system for guiding artists to paint using traditional media and tools. The enabling technology is a multi-projector display capable of controlling the appearance of an artist’s canvas. Artists are guided by this display-on-canvas to execute painting techniques. The artist paints according to a linear process of painting by numbers, one layer at a time. Ea...