background: influenza a (h1n1) pandemic is recently threatening the health of world's population. non-pharmaceutical measures are important to prevent the spread of influenza a (h1n1) and to prevent a pandemic. effective influenza pandemic management requires understanding of the factors influencing preventive behavioral changes. this study determined the status of preventive behaviors regardin...

background: the healthcare and socio-economic burden resulting from influenza a (h1n1) pdm09 in spain was considerable. our aim was to estimate and compare the management (resource utilization) and economic healthcare impact in an at-risk group of unvaccinated pregnant women with an unvaccinated group of non-pregnant woman of childbearing age (15-44 yr old). methods: we addressed this question ...

background: the clinical manifestations and outcome of influenza infection differ between various patients in the world. the purpose of this study was to assess the clinical manifestations of patients with confirmed or suspected novel h1n1 flu infection in sari, north of iran. methods: from september 2009 to january 2010, the patients’ data were collected by retrospective chart review of medica...

background and aims: influenza a viruses are important pathogens for humans especially in pandemic episodes. two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza a virus infections. however, single amino acid substitutions in the m2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...

conclusions the prevalence of pandemic influenza viruses in recent years has caused financial losses as well as mortalities around the world. this shows the importance of the rapid diagnosis of common serotypes in our society. using real-time rt-pcr is recommended for the early diagnosis and the rapid identification of the individuals infected with pandemic influenza virus. background timely di...

Background and Aims: Influenza A viruses are important pathogens for humans especially in pandemic episodes. Two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza A virus infections. However, single amino acid substitutions in the M2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...

background emergence of a novel swine-origin influenza a (h1n1) pandemic since 2009 attracted the attention of scientists to characterize epidemiological features and clinical manifestations of this disease in comparison to seasonal flu in different parts of the world. objectives the goal of this investigation was to compare these features in confirmed cases of swine-origin influenza a (h1n1) a...

Levels of preexisting antibodies to the hemagglutinin of pandemic influenza A(H1N1) 2009 (hereafter pandemic H1N1) virus positively correlate with age. The impact of contemporary seasonal influenza vaccines on establishing immunity to other pandemic H1N1 proteins is unknown. We measured serum antibodies to the neuraminidase (NA) of pandemic H1N1 in adults prior to and after vaccination with sea...

To estimate effectiveness of seasonal trivalent and monovalent influenza vaccines against pandemic influenza A (H1N1) 2009 virus, we conducted a test-negative case-control study in Victoria, Australia, in 2010. Patients seen for influenza-like illness by general practitioners in a sentinel surveillance network during 2010 were tested for influenza; vaccination status was recorded. Case-patients...