This study aimed to evaluate in-vitro antioxidant activities of hydroethanolic extract of leaves of Cynara scolymus L., Cupressus sempervirens L., and Eugenia jambolana Lam comparing with ascorbic acid, and their correlation with in-vivo hepatoprotective activity in rat model of paracetamol-induced hepatotoxicity, comparing with silymarin as reference agents. In-vitro study revealed that the te...

OBJECTIVE To compare the efficacy of enteral paracetamol and intravenous indomethacin for closure of patent ductus arteriosus (PDA) in preterm neonates. DESIGN Randomized controlled trial. SETTING Level III neonatal intensive care unit. PARTICIPANTS 77 preterm neonates with birth weight ?1500 g and PDA size ?1.5 mm, with left to right ductal flow with left atrium to aortic root ratio >1.5...