Electrical stimulation of the subthalamic nucleus is an established treatment for patients with advanced Parkinson’s disease with pharmacologically un responsive fl uctuations. Compared with pharmacological treatment, subthalamic neurostimulation signifi cantly improves motor symptoms, particularly during the phases of poor response to drug treatment, and reduces the severity of dyskinesias. Im...

In this review report, current possibilities of evaluation of quality of life in Parkinson's disease have been critically presented. Health Related Quality of Life (-HRQoL) comprises a wide spectrum of consequences of the disease. Measurement of quality of life has become increasingly relevant as an outcome parameter, especially in long-term trials. Most of the available QoL instruments depend ...