Synchronization processes are of crucial importance for brain function. Well-coordinated synchrony within and between neuronal populations appears to be an important mechanisms for neuronal signaling and information processing. In contrast, pathologically strong synchronization may severely impair brain function. For instance, resting tremor in Parkinson’s disease is caused by a synchronized po...

Swallowing difficulties and constipation were included in the first description of Parkinsons ́s syndrome from 1817 (Parkinson 1817). Since then, numerous studies have confirmed the magnitude of symptoms and addressed their pathophysiology. In spite of this, much remains to be determined and treatment of gastrointestinal dysfunction in Parkinson ́s disease (PD) is often unsatisfactory. Parkinson ́...

The paper details the construction of a clinical decision support system which is the integral part of the ParkinsonCheck application. ParkinsonCheck is an app for smart phones built to detect signs of Parkinsons disease (PD) and essential tremor (ET), which is the main differential diagnosis from PD in the early stage of the disease. The application is based on spirography (spiral drawing) and...